Normal Flora Flashcards
When does colonization begin?
At birth and stabilizes in 3-4 years
Microbiome compartments
Mouth
Nose
Intestines
Vagina
Skin
The human microbiome contributes to heath through
Healthy immune function
Healthy metabolism
Healthy barrier function
Dysbiosis of the human microbiome can lead to
Inflammatory disease
Metabolic disease
Susceptibility of opportunistic pathogens
Confounding variables to gut microbiota
Alcohol consumption
Bowel movement quality
C diff exemplifies the importance of _ served by normal flora and the _
Ecological barrier function
Diagnostic challenge of differentiating between the detection of normal colonizing bacteria versus the causative agent of disease
_ exemplifies multiple risk factors for infection by normal flora
Hematopoietic stem cell transplant
Catheritization- localized invasion
Neutropenia- disruption of immunologic barrier
Chemotherapy injuries to mucosal epithelium- disruption of physical barrier
Antibiotics- disruption of ecological barrier