Normal Flora Flashcards

1
Q

When does colonization begin?

A

At birth and stabilizes in 3-4 years

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2
Q

Microbiome compartments

A

Mouth
Nose
Intestines
Vagina
Skin

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3
Q

The human microbiome contributes to heath through

A

Healthy immune function
Healthy metabolism
Healthy barrier function

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4
Q

Dysbiosis of the human microbiome can lead to

A

Inflammatory disease
Metabolic disease
Susceptibility of opportunistic pathogens

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5
Q

Confounding variables to gut microbiota

A

Alcohol consumption
Bowel movement quality

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6
Q

C diff exemplifies the importance of _ served by normal flora and the _

A

Ecological barrier function
Diagnostic challenge of differentiating between the detection of normal colonizing bacteria versus the causative agent of disease

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7
Q

_ exemplifies multiple risk factors for infection by normal flora

A

Hematopoietic stem cell transplant
Catheritization- localized invasion
Neutropenia- disruption of immunologic barrier
Chemotherapy injuries to mucosal epithelium- disruption of physical barrier
Antibiotics- disruption of ecological barrier

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