Misc Viruses Flashcards

1
Q

Adenovirus

A

DNA
naked capsid

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2
Q

Adenovirus ilness

A

cold or flu like symptoms
pink eye
bronchitis
pneumoia
diarrhea
gasteroenteritis

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3
Q

Adenovirus transmission

A

respiratory droplets
fecal-oral route formites
formites

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4
Q

Adenovirus diagnosis

A

molecular testing (PCR)
antigen testing

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5
Q

RSV

A
  • RNA virus
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6
Q

RSV is transmitted through

A

direct contact

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7
Q

RSV causes

A

upper respiratory infection
bronchiolitis
palivizumab
lethargy
apnea
fever
funny nose
caugh
headache
sore throa

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8
Q

RSV high risk groups

A

<6 months or >65 years
premature infants
congenetal heart or lung disease
neuromuscular disease
transplant recipients

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9
Q

RSV prevention

A

palivizumab: prophylatic humanized monoclonal antibody against RSV F glycoprotein

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10
Q

Picornavirus

A

+ RNA
poliovirus

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11
Q

poliovirus causes

A

poliomyelitis

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12
Q

poliomyelitis pathogenesis

A

enters through mouth
replicates in pharynx and GI tract
hematologic spead to lymphatics and CNS
viral spread along nerve fibers
destruction of motor neurons

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13
Q

polio symptoms nonparalytic disease

A

fever
sore throat
headache
vomiting
fatigue
back pain
neck pain
muscle weakness

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14
Q

polio symptoms paralytic disease

A

loss of reflexes
severe mucles aches and weakness
loose and floppy limbs

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15
Q

poliovirus destroys

A

nevere cells in spinal cord leading to muscle wasting and paralysis

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16
Q

poliovirus causes _ paralysis

A

flaccid

17
Q

Coxsackie

A

hand foot and mouth disease

18
Q

Coxsackie symptoms

A

cold like illness
gasteroenteritis
myocarditis
pericarditis
acult flaccid myelitis
vesicular lesions on hands, feet, and mouth

19
Q

Rhabdovirus

A

-RNA

20
Q

Rhabdovirus causes

A

Rabies (bat, skunk, racoon, fox, mongoose)
Dogs are most common

21
Q

Rabies process

A

innocualtion
replication in muscle
enters perephrial nervous sytem
passive ascent via sensory fibers
replication in dorsal ganglion
ascent to spinal cord
infection of spinal cord, brainstem, cerebellum, and other brain structures
descending infection via nervous system to eye, salivary glands, skin, and other organs

22
Q

rabies prevention in high risk

A

vaccine series

23
Q

post exposure care

A

immediate wound cleaning
rabies immunoglobulin
rabies vaccine series (4 doses for non-immunized, 2 doses for immunized)

24
Q

Poxvirus

A

Enveloped ds-DNA virus

25
Q

Smallpox is caused by

A

variola virus

26
Q

Smallpox is spread via

A

respiratory droplets or direct contact from lesion (all at same stage)

27
Q

Smallpox vaccine

A

live attenuated
vaccine has been discontinues
potential agent of bioterrorism