Misc Viruses Flashcards
Adenovirus
DNA
naked capsid
Adenovirus ilness
cold or flu like symptoms
pink eye
bronchitis
pneumoia
diarrhea
gasteroenteritis
Adenovirus transmission
respiratory droplets
fecal-oral route formites
formites
Adenovirus diagnosis
molecular testing (PCR)
antigen testing
RSV
- RNA virus
RSV is transmitted through
direct contact
RSV causes
upper respiratory infection
bronchiolitis
palivizumab
lethargy
apnea
fever
funny nose
caugh
headache
sore throa
RSV high risk groups
<6 months or >65 years
premature infants
congenetal heart or lung disease
neuromuscular disease
transplant recipients
RSV prevention
palivizumab: prophylatic humanized monoclonal antibody against RSV F glycoprotein
Picornavirus
+ RNA
poliovirus
poliovirus causes
poliomyelitis
poliomyelitis pathogenesis
enters through mouth
replicates in pharynx and GI tract
hematologic spead to lymphatics and CNS
viral spread along nerve fibers
destruction of motor neurons
polio symptoms nonparalytic disease
fever
sore throat
headache
vomiting
fatigue
back pain
neck pain
muscle weakness
polio symptoms paralytic disease
loss of reflexes
severe mucles aches and weakness
loose and floppy limbs
poliovirus destroys
nevere cells in spinal cord leading to muscle wasting and paralysis
poliovirus causes _ paralysis
flaccid
Coxsackie
hand foot and mouth disease
Coxsackie symptoms
cold like illness
gasteroenteritis
myocarditis
pericarditis
acult flaccid myelitis
vesicular lesions on hands, feet, and mouth
Rhabdovirus
-RNA
Rhabdovirus causes
Rabies (bat, skunk, racoon, fox, mongoose)
Dogs are most common
Rabies process
innocualtion
replication in muscle
enters perephrial nervous sytem
passive ascent via sensory fibers
replication in dorsal ganglion
ascent to spinal cord
infection of spinal cord, brainstem, cerebellum, and other brain structures
descending infection via nervous system to eye, salivary glands, skin, and other organs
rabies prevention in high risk
vaccine series
post exposure care
immediate wound cleaning
rabies immunoglobulin
rabies vaccine series (4 doses for non-immunized, 2 doses for immunized)
Poxvirus
Enveloped ds-DNA virus
Smallpox is caused by
variola virus
Smallpox is spread via
respiratory droplets or direct contact from lesion (all at same stage)
Smallpox vaccine
live attenuated
vaccine has been discontinues
potential agent of bioterrorism