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My2 MSK > Spondyloarthropathies > Flashcards

Spondyloarthropathies Flashcards

1
Q

what are spondyloarthropathies

A

inflammatory arthritides involving spine and joints, sero-negative meaning no rheumatoid factor

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2
Q

what gene is present in Spondyloarthropathies and what other conditions is it seen is

A

HLA B27, Crohn’s

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3
Q

what are the 4 Spondyloarthropathies subgroups

A

ankylosing spondylitis, psoriatic arthritis, reactive arthritis, enteropathic arthritis

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4
Q

what joints are commonly affected in Spondyloarthropathies

A

sacroiliac and spinal

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5
Q

what general features are present in Spondyloarthropathies

A

enthesitis (tendon), arthritis (asymmetrical), dactylitis (sausage fingers), occular inflamm

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6
Q

what is ankylosing spondylitis

A

verterbral discs fuse together, meaning it cant straighten out

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7
Q

who gets ankylosing spondylitis

A

men aged 20

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8
Q

what are the symptoms of ankylosing spondylitis

A

sacrioiliac joint pain, spinal morning stiffness that improves with exercise, no peripheral arthritis, shoulder and hip involvement

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9
Q

what are the 5 symptoms used in diagnostic criteria of increasing severity ankylosing spondylitis

A

limited lumbar movement, lower back pain for 3 months (not relieved on rest), reduced, reduced chest expansion, bilateral sacriolitis, unilateral sacroiliitis

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10
Q

what test can be done for ankylosing spondylitis

A

schober test

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11
Q

what imaging is used for ankylosing spondylitis

A

X ray and MRI

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12
Q

along side >3 months back pain and 45> age, what must be present to diagnose ankylosing spondylitis

A

sacroilitiis on imaging + 1 SpA feature OR HLA B2& positive + 2 SpA features

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13
Q

what 7 A’s are associated with ankylosing spondylitis

A

anterior uveitis, aortic valve involvement, apical pulm fibrosis, asymptomatic enteric mucosal inflamm, amyloidosis, achilles tendonitis, Atlanto-axial subluxation

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14
Q

how do you treat ankylosing spondylitis (mild - severe)

A

physio, NSAID’s, anti TNF eg infliximab (DMARDs if peripheral joint involvement)

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15
Q

what clinical features are there in psoriatic arthritis (7)

A

DIP involvement, multiple joints, sacroiliitis, dactylitis, nail pitting/ onycholysis, enthesitis, eyes

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16
Q

what tendons are affected in psoriatic arthritis

A

achilles and plantar fascia

17
Q

how do you diagnose psoriatic arthritis

A

HISTORY + EXAM bloods: inflamm markers, X ray: osteolysis, enthesitis

18
Q

how do you treat psoriatic arthritis (mild –> severe)

A

NSAIDs, steroid injections, DMARDs (methotrexate), anti TNFa if failed methotrexate

19
Q

what is reactive arthritis

A

inflammation of synovium induced by infection - no infection in joint however

20
Q

what infections commonly cause reactive arthritis

A

chlamydia, salmonella, shigella

21
Q

what symptoms are present in reactive arthritis (7)

A

arthritis (pain, stiffness, function), Reiters syndrome, fever, fatigue, malaise, enthesitis, mucocutaneous legions

22
Q

what is reiters syndrome

A

urethritis, uveitis, arthritis

23
Q

what mucocutaneous legions can be present in reactive arthritis

A

nail dystrophy, keratoderma blennorrhagica (feet plaques), oral painless ulcers

24
Q

how do you diagnose reactive arthritis

A

bloods: inflam, FBC, culture, joint aspiration, X ray

25
Q

how do you treat reactive arthritis

A

AB’s, NSAIDs, DMARD’s steroids - can resolve spontaneously

26
Q

what is enteropathic arthritis

A

associated with IBD, commonly affecting lower limb eh sacriolitis

27
Q

what are the symptoms of enteropathic arthritis (6)

A

IBD symptoms (stools), weight loss, fever, uveitis, aphthous ulcer, enthesitis (achilles/ plantar fascia)

28
Q

what invx are done for enteropathic arthritis

A

endoscopy, aspiration, inflamm marers, USS

29
Q

how do you treat enteropathic arthritis (mild –> severe)

A

IBD treatment, analgesia, steroids, DMARDs, anti TNF (NSAIDs can cause peptic ulcers

My2 MSK (29 decks)

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