histology Flashcards

1
Q

describe skeletal muscle (6)

A

straited, unbranched, multinulceated, nucleus pushed to membrane (sarcolemma), long cylinders, have satellite stem cells (mane new muscle)

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2
Q

what are muscle fibres grouped into

A

fascicles

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3
Q

what is the connective tissue that surrounds muscle as a whole called

A

epimysium

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4
Q

what is the connective tissue that surrounds single muscle fascicle as a whole called

A

perimysium

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5
Q

what is the connective tissue that surrounds muscle fibre as a whole called

A

endomysium

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6
Q

how is muscle organised

A

muscle –> fibres (cells) –> fascicles –> myofibril –> sarcomere

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7
Q

what are sarcomeres and where do they extend between

A

units of contraction, between Z lines which cause striations

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8
Q

what is a motor unit

A

a nerve and all the muscle fibres it innervates (alpha?)

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9
Q

where do axons of motor unit terminate

A

neuromuscular synapses

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10
Q

what are the 3 fibre types

A

type I (oxidative slow type), type IIa (intermediate), type IIb (anaerobic fast)

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11
Q

describe cartilages rigidness, permeability and vascular supply

A

semi-rigid, permeable, avascular

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12
Q

how are cartilage cells nourished

A

through ECM called lacuna that they secrete

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13
Q

what is the lacuna made of

A

75% water, 25% type II collagen and proteoglycan

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14
Q

what are the 3 types of cartilage

A

hyaline, elastic, fibrocartilage

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15
Q

what is hyaline cartilage

A

glassy, blue-white and transparent, common

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16
Q

what is elastic cartilage

A

light yellow, elastic and flexible

17
Q

what is fibro cartilage

A

hybrid of tendon and hyaline, type 1 collage with chondrocytes, white

18
Q

what is the outside, shaft/ diaphysis made up of in bone

A

dense cortical bone

19
Q

what is the end of bones/ epiphysis made of

A

cancellous or trabecular bone

20
Q

how does bone receive vascular supply

A

haversian’s channels (except trabecular bone)

21
Q

what is bone grouped into

A

osteons

22
Q

what are osteoprogenitors

A

stem cells that make osteoblasts

23
Q

what are osteoblasts

A

bone forming cells

24
Q

what do osteoblasts secrete

A

collagen, GAG’s, proteogylcans to make osteoid which is mineralised to bone

25
Q

what are osteoclasts

A

break down bone