orthopaedics: osteomyelitis and MSK infections Flashcards

1
Q

what is osteomyelitis

A

infection of bone including compact bone, spongy bone and bone marrow

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2
Q

what infective organisms normally cause osteomyelitis

A

occasionally fungal, usually bacterial: staph A (90%), H influenza, salmonella

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3
Q

how does osteomyelitis spread

A

haematological

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4
Q

what are the symptoms of osteomyelitis

A

fever, localised pain and tenderness over bone, erythema

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5
Q

what is an involucrum

A

new bone forming around dead, necrotic bone

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6
Q

what investigations are done in osteomyelitis

A

MRI>xray, blood cultures, biopsy and culture

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7
Q

who normally gets acute osteomyelitis

A

children (boys) and immunocompromised

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8
Q

why are children more likely to get osteomyelitis

A

metaphysis has torturous vessels with slow flow that can accumulate bacteria

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9
Q

what can subacute osteomyelitis lead to

A

brodies abscess

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10
Q

how do you treat acute osteomyelitis

A

IV AB, surgical drain of abscess, if AB fails then cultures and washout of infected bone

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11
Q

how do you get chronic osteomyelitis

A

untreated acute,

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12
Q

where does chronic where does it commonly affect commonly affect

A

axial skeleton (spine/ pelvis)

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13
Q

how do you manage chronic axial skeleton (spine/ pelvis)

A

surgical debridement and biopsy, bone grafting, long hospital recovery and IV AB’s

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14
Q

what should be avoided in osteomyelitis

A

emperic AB’s

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15
Q

who can get Haematogenous vertebral osteomyelitis

A

children, post trauma, IV drugs, diabetics, central lines

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16
Q

what is gold standard diagnosis in osteomyelitis

A

bone biopsy

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17
Q

what is Haematogenous vertebral osteomyelitis

A

infection of bone from blood spread elsewhere in body

18
Q

how do you manage Haematogenous vertebral osteomyelitis

A

drain and debride, avoid emperic AB’s unless sepsis, antimicrobials for 6 weeks

19
Q

name 3 unusual osteomyelitis

A

sickle cell, Gaucher’s disease, SAPHO, CRMO

20
Q

what causes TB osteomyelitis

A

blood spread from reactivated TB, usually affects spine

21
Q

what disease is common in TB osteomyelitis and what are the symptoms

A

Pott’s disease, asymptomatic

22
Q

who is at risk of prosthetic joint infections

A

RA, diabetes

23
Q

what are symptoms of prosthetic joint infections

A

haemotoma, puss,, tender, pain, loss of function

24
Q

what organisms cause prosthetic joint infections

A

normally staph epidermis, staph A, e.coli, pseudomonas, fungal

25
how do you manage prosthetic joint infections
remove joint, vancomycin and replace
26
how do you get septic arthritis
direct invasion from penetration which then spreads through blood
27
what organisms commonly cause septic arthritis
staph A, strep, N gonnorhea, H influ (kids), e.coli (elderly, IV drug users)
28
what are symptoms of septic arthritis
red, hot, swollen, sore, not working, fever, systemically V unwell
29
what viral causes can cause arthritic sepsis
hep B, parovirus
30
how do you treat septic arthritis
presumed staph A --> fluclox, under 5 ceftriaxone (h influ), surgical wash out (avoid empiric ABs)
31
what organisms cause pyomyositis
90% staph, pseudomonas, B haemolystic strep, enterocoous
32
what causes tetanus and what type of bacteria is it
clostridium tetani, gram +ive anaerobic rod
33
what do toxins of tetanus do
cause spastic paralysis eg lockjaw
34
how do you treat tetanus
penicillin and metro, vaccines
35
what antibiotic should be given to staph and strep
fluclox
36
what antibiotic should be given to staph and strep if penicillin allergy
vancomycin
37
what AB is given to staph epi
vanco
38
what AB is given to strep pyogens
doxy
39
what is given to gram -ive
clindamycin
40
what is given to anaerobes
metro