Spondyloarthropathies Flashcards

1
Q

What is a spondyloarthropathy?

A

A family of inflammatory arthritides involving the spine and joints in HLA B27 positive individuals

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2
Q

Give some conditions associated with HLA B27

A

Ankylosing spondylitis
Reactive arthritis
Crohn’s

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3
Q

Is HLA B27 a useful screening test on its own?

A

No

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4
Q

What are the subgroups of spondyloarthritis?

A

Ankylosing spondylitis
Psoriatic arthritis
Reactive arthritis
Enteropathic arthritis

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5
Q

What are some shared rheumatological features of spondyloarthropathies?

A

Spinal involvement

Dactylitis (sausage digits)

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6
Q

What is ankylosing spondylitis?

A

A chronic inflammatory disorder primarily affecting the spine

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7
Q

What is the hallmark pain of ankylosing spondylitis?

A

Pain and stiffness around buttocks

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8
Q

Give some clinical features of ankylosing spondylitis

A

Back pain
Enthesitis
Aortic regurgitation
Pulmonary fibrosis

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9
Q

What occurs in a patient’s spine in ankylosing spondylitis?

A

The vertebrae fuse together

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10
Q

Give some examinations that can be carried out for ankylosing spondylitis

A

Chest expansion
Schober test
Occiput to wall

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11
Q

X-rays are useful early diagnostic tools in ankylosing spondylitis. True/false?

A

False

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12
Q

How is ankylosing spondylitis treated primarily?

A

Physiotherapy

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13
Q

What drugs can be used in ankylosing spondylitis?

A

NSAIDs
DMARDs
Anti TNF

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14
Q

What is psoriatic arthritis?

A

Inflammatory arthritis associated with psoriasis

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15
Q

Give some clinical features of psoriatic arthritis

A

Sacroilitis
Nail involvement
Dactylitis

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16
Q

Rheumatoid factor is negative in psoriatic arthritis. True/false?

A

True

17
Q

What drugs are used to treat psoriatic arthritis?

A

NSAID
Corticosteroids
DMARDs
Anti TNF

18
Q

What is reactive arthritis?

A

An infection induced systemic illness characterised by an inflammatory synovitis

19
Q

Which type of infection commonly cause reactive arthritis?

A

Urogenital

Enterogenic

20
Q

HLA B27 is positive in reactive arthritis. True/false?

A

True

21
Q

What are some clinical features of reactive arthritis?

A

Enthesitis
Monocutaneous lesions
Conjunctivitis

22
Q

How is reactive arthritis treated?

A

NSAIDs
Antibiotics
DMARDs

23
Q

What is enteropathic arthritis?

A

Arthritis associated with inflammatory bowel disease

24
Q

What are the clinical symptoms of enteropathic arthritis?

A

Loose watery stool with mucous and blood
Weight loss
Skin involvement
Enthesitis

25
Q

How can enteropathic arthritis be investigated?

A

Upper and lower GI endoscopy

Joint aspirate

26
Q

How is enteropathic arthritis treated?

A
Treat IBD
Analgesics
Steroids
DMARDs
Anti TNF