Spondyloarthropathies Flashcards
What is a spondyloarthropathy?
A family of inflammatory arthritides involving the spine and joints in HLA B27 positive individuals
Give some conditions associated with HLA B27
Ankylosing spondylitis
Reactive arthritis
Crohn’s
Is HLA B27 a useful screening test on its own?
No
What are the subgroups of spondyloarthritis?
Ankylosing spondylitis
Psoriatic arthritis
Reactive arthritis
Enteropathic arthritis
What are some shared rheumatological features of spondyloarthropathies?
Spinal involvement
Dactylitis (sausage digits)
What is ankylosing spondylitis?
A chronic inflammatory disorder primarily affecting the spine
What is the hallmark pain of ankylosing spondylitis?
Pain and stiffness around buttocks
Give some clinical features of ankylosing spondylitis
Back pain
Enthesitis
Aortic regurgitation
Pulmonary fibrosis
What occurs in a patient’s spine in ankylosing spondylitis?
The vertebrae fuse together
Give some examinations that can be carried out for ankylosing spondylitis
Chest expansion
Schober test
Occiput to wall
X-rays are useful early diagnostic tools in ankylosing spondylitis. True/false?
False
How is ankylosing spondylitis treated primarily?
Physiotherapy
What drugs can be used in ankylosing spondylitis?
NSAIDs
DMARDs
Anti TNF
What is psoriatic arthritis?
Inflammatory arthritis associated with psoriasis
Give some clinical features of psoriatic arthritis
Sacroilitis
Nail involvement
Dactylitis
Rheumatoid factor is negative in psoriatic arthritis. True/false?
True
What drugs are used to treat psoriatic arthritis?
NSAID
Corticosteroids
DMARDs
Anti TNF
What is reactive arthritis?
An infection induced systemic illness characterised by an inflammatory synovitis
Which type of infection commonly cause reactive arthritis?
Urogenital
Enterogenic
HLA B27 is positive in reactive arthritis. True/false?
True
What are some clinical features of reactive arthritis?
Enthesitis
Monocutaneous lesions
Conjunctivitis
How is reactive arthritis treated?
NSAIDs
Antibiotics
DMARDs
What is enteropathic arthritis?
Arthritis associated with inflammatory bowel disease
What are the clinical symptoms of enteropathic arthritis?
Loose watery stool with mucous and blood
Weight loss
Skin involvement
Enthesitis
How can enteropathic arthritis be investigated?
Upper and lower GI endoscopy
Joint aspirate
How is enteropathic arthritis treated?
Treat IBD Analgesics Steroids DMARDs Anti TNF