spermatogenesis and male infertility Flashcards

1
Q

what chromosome has the sex determining region on it?

A

Y chromosome

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2
Q

what are the 2 primitive genital tracts?

A

wolffian and mullerian

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3
Q

in a male what primitive tract forms the genitals

A

wolffian ducts

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4
Q

in a female what primitve tract forms the genitals

A

mullerian ducts

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5
Q

what cells secrete testosterone

A

leydig cells

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6
Q

where does spermatogeneis take place

A

seminiferous tubules in testes

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7
Q

roles of the sertoli cells

A
form blood- testes barrier
provide nutrients for developing cells
secrete seminiferous tubule fluid
secrete andorgen binding globulin
secrete inhibin and activin hormone
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8
Q

what is the role of gonadotrophin releasing hormone?

A

stimulates anterior pituitary to release LH and FSH

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9
Q

what does LH do?

A

acts on leydig cells which secrete testosterone

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10
Q

what does FSH do?

A

acts on sertoli cells to enhance spermatogenesis

regulates negative feeback by acting on sertoli cells to secrete inhibin

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11
Q

function of epididymis and vas deferens

A

exit route from testes to urethra, concentrate and store sperm, site for sperm to mature

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12
Q

function of seminal vesicles

A

produce semen in ejqaculatory duct

supplu fructose and prostaglandins and fibrinogen

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13
Q

function of prostate

A

produce alkaline fluid and clotting enzymes to clot semen in female

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14
Q

function of bulbourethral gland

A

secrete mucus to act as lubricant during sex

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15
Q

erection is under what autonomic control

A

parasympathetic

ejaculation is sympathetic

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16
Q

causes of male infertiloty

A

low sperm count, qaulity, motiloty etc

obstruction to vas deferens

testicular failure- klinefelters, chemo

endo causes- diabetes, thyroid problems,acromegaly, cushings

erectile difficulty- spinal cord injury, diabetes, psychosexual

17
Q

effect of excess alcohol on sperm count?

A

reduces sperm count