microbiology Flashcards

1
Q

what organism predominates in the healthy vagina

A

lactobacillus spp

also strep B and viridans
and candida

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2
Q

other name for candida infection?

A

vaginal thrush

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3
Q

predisposing factors for candida infection?

A

recent antibiotics treatment
high oestrogen level ( pill pregnancy)
poorly controlled diabetes
immunocompromised patients

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4
Q

how does candida normally present

A

intense itch
white vaginal discharge

red vagina

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5
Q

most candida infecctions are caused by what?

A

candida albicans

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6
Q

how do you diagnose thrush?

A

clinical diagnosis

can do high vaginal swab for culture

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7
Q

how do you treat candida

A

topical clotrimazole cream or pessary

oral fluconazole

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8
Q

symptoms of bacterial vaginosis

A

thin water fishy smelling discharge

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9
Q

what tends to cause bacterial vaginosis

A

Gardnerella vaginalis/ Mobiluncus sp

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10
Q

is pH raised or low in bacterial vaginosis

A

high (> 4.5)

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11
Q

what lab tests is there for bacterial vaginosis

A

high vaginal swab can be taken and sent lab and excamined

CLUE CELLS present

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12
Q

how do you treat bacterial vaginosis

A

oral metronidazole

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13
Q

what is acute bacterial prostatitis?

A

similar symptoms to UTI in men. but may have lower abdo pain, perineal/penile pain

tender prostate in examination

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14
Q

how do you treat bacterial prostatitis?

A

ciprofloxacin for 28 days

or trimethoprim

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15
Q

most common STI in UK?

A

chlamydia

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16
Q

what does chlamydia infect?

A

urethra, eyes, throat, rectum, endocervix

17
Q

what doesnt it stain with gram stain

A

does stain because so peptidoglycan in wall

18
Q

how do you treat chlamydia

A

azithomycin

19
Q

what does gonorhhoeae infect?

A

urethra, eyes, throat, rectum, endocervix

20
Q

how would you describe neisseria gonorrhoee

A

gram negative intracellular diplococcus

looks like 2 kidney beans facing each other

21
Q

how do you diagnosis clamydia and /or gonorrhoeaa

A

in males - first pass urine for nucleic acid amplififcation tests (NAATs) and/ or PCR

in females- high vaginla swan or vulvo vaginal swab or endocervical swab

also rectal and throat swabs

and eye swabs

22
Q

how do you treat gonorrhoea?

A

IM ceftriaxone and oral azithromycin

23
Q

what causes syphilis?

A

Treponema pallidum

24
Q

does treponema stain with gram stain?

A

no

25
Q

how do you diagnose syphilis?

A

PCR and antibodies to T. pallidum in blood

also IgG IgM

26
Q

how do you treat symphilis?

A

penicllin!! injecting prepartions can be made

27
Q

most common viral STI?

A

genital warts

28
Q

what causes genital warts?

A

HPV

29
Q

how do you treat genital warts?

A

cryotherapy

podophyllotoxin cream/lotion

30
Q

what causes genital herpes?

A

herpes simplex virus type 1 (also causes cold sores) and type 2

31
Q

how do you diagnose genital herpes?

A

swab a blister for PCR

32
Q

how do you treat genital herpes

A

aciclovir

pain relief

33
Q

what is trichomonas vaginalis?

A

a single celled protozoal parasite

causes vag discharge and irriation in females

34
Q

how do you treat trichomonas vaginalis?

A

oral metronidazole

35
Q

how do you treat pubic lice?

A

malathion lotion