prescribing in pregnancy

Question 1

do most drugs cross the placenta

Answer 1

YES

except large molecular weight heparin

Question 2

are most drugs licened for use in pregancy?

Answer 2

no- but you can still use them.

Question 3

do albumin levels fall in pregnancy

Answer 3

yes

Question 4

why does the excretion of renally excreted drugs increase during pregnany?

Answer 4

due to increased GFR

Question 5

what might absorption be affected by?

Answer 5

morning sickness

Question 6

400mcg off folic acid should be taken when?

Answer 6

3 months before conception to 12 weeks into pregnancy

Question 7

what is the period of greatest teratogenic risk?

Answer 7

4th-11th weeks

teh key organs develop in this window

Question 8

what can warfarin cause?

Answer 8

limb and facial defects

Question 9

what can AICi and ARBS do>

Answer 9

renal hypoplasia

Question 10

and can anti-epileptics do?

Answer 10

neural tube defects

heart , face and limb defects

Question 11

what can lithium do?

Answer 11

cardiovascular defects

Question 12

what can opiates causes

Answer 12

reps depression

Question 13

what drugs can cause withdrawel syndrome for teh baby after birth?>

Answer 13

opiates and SSRI

Question 14

what epleipsy drugs should you avoid?

Answer 14

valproate and phenytoin

the benefits of treatment outweights the risk on most cases of the other drugs- monotherapy is preferred

Question 15

what diabetic medication is not safe to take>

Answer 15

sulfonylureas- convert to insulin

Question 16

what should you treat high BP with in pregnancy?

Answer 16

labetalol
or

methyldopa
nidefipine MR

Question 17

for nausea and vomiting what can you give?

Answer 17

cyclizine

Question 18

what can you give for pain?

Answer 18

paracetamol

Question 19

what can you give for heart burn?

Answer 19

antacids

Question 20

how do you treat venous thromboembolism in pregnancy

Answer 20

low molecular weight heparin