Spectrum of Human Diseases Flashcards
What are the 4 aspects of disease?
- Etiology(Cause)
- Pathogenesis(Development)
- Molecular and Morphologic changes–Biochemical and structural alterations induced in the cells and organs
- Clinical manifestations –Functional consequences of these changes
___ is a state of complete physical, mental and social well-being and not merely the absence of disease or infirmity
a process of continuous adjustment to the changing demands of living and of the changing meanings we give to life
the slowest rate at which one can die!
Health
Any abnormal condition that may impair bodily function, cause discomfort, social problems, death
•May include –Injuries–Disabilities–Disorders–Syndromes–Infections–Alterations of behavior–Atypical variations of structure and function What is
Disease
______ path:
–diagnosis of disease based on the examination of tissues and cells
–Surgical pathology–Cytopathology–Autopsy pathology–Forensic pathology
Anatomic pathology
_____ path:
(laboratory medicine) –diagnosis of disease based on the analysis of body fluids–Clinical chemistry–Hematopathology–Blood banking and transfusion medicine –Medical microbiology–Medical cytogenetics–Immunology
Clinical pathology
- Specialty of dentistry and discipline of pathology that deals with the nature, diagnosis, and management of diseases affecting the oral and maxillofacial regions. •The science that investigates the causes, processes, and effects of these diseases.
- The practice includes the diagnosis of disease using clinical, radiographic, biochemical, microscopic, molecular or other examinations; and the treatment and/or management of patients.
Oral Path
___ is a bridge btwn basic science and patient care
Pathology
_____ is the basis of all disease
Pathology
_____ path: the basic reactions of cells and tissues to the abnormal stimuli that underlie all diseases
General pathology
______ path: the specific responses of organs and tissues to stimuli
Systemic pathology
A _____ is any clinical or molecular abnormality
lesion
___ cancer is one of the most common metastatic cancers in the mandible
Breast cancer
The ______ of a disease ideally should give a clue to the cause or the organ system involved
name
For florid cemento-osseous dysplasia, what type of people are most affected?
African american females
______ refers to the disease state of an individual, or the incidence of illness in a population.
Morbidity
______: Simultaneous presence of two or more medical conditions
Comorbidity
_______ refers to the state of being mortal, or the incidence of death (number of deaths) in a population.
Mortality
–Definition: Identifying the nature or cause of some phenomenon
Diagnosis
–Definition: A prediction about how something (as an illness) will develop
Prognosis
: objective something clinician sees
Sign
:subjective; something the patient tells you
Symptom
•A sign whose presence means that a particular disease is present beyond any doubt (a sure sign)
Pathognomonic sign
: the study of the cause of a disease process
•Etiology
the mechanism of disease development
•Pathogenesis:
: the structural changes induced in cells and organs
•Morphologic changes
: the functional consequences of the morphologic changes
•Clinical significance
In ______, CFTR gene undergoes mutation in phenylalanine
CF
What is the average life expectancy in CF?
37
How is CF diagnosed?
Sweat chloride test
Cherubism is an autosomal dominant, Garner syndrome, and AI are all a ______ disease
Developmental
_____ is an autosomal dominant developmental disease: familial intestinal polyposis syndrome
Gardner syndrome
Primary Herpetic gingivostomatitis, Pseudomembranous candidiasis, histoplasmosis are all _____ diseases
Infectious disease
Acromegaly and hypothyroidism are all _____ diseases
Metabolic
SCC, metastatic bronchogenic carcinoma, kaposi sarcoma, acute leukemia, ameloblastoma, neurofibromatosis, adenoid cystic carcinoma, and hemangioma, are all _____ diseases
Neoplastic
Recurrent aphthous stomatitis, mucous membrane pemphigoid, and autoimmune thrombocytopenic purpura are all _____ diseases
Immune-mediated
Pyogenic granuloma and gingival hyperplasia are all _____ diseases
Reactive
