Diseases of Salivary Glands Flashcards
The following are _____ salivary glands:
Parotid
Submand
Sublingual
Major
The following are \_\_\_\_\_ salivary glands: Palate Buccal mucosa Tongue Floor of mouth Labial mucosa Retromolar pad Oropharynx
Minor
In regards to serous or mucous acini, what is the parotid gland made up of?
Serous acini
In regards to serous or mucous acini, what is the submand gland made up of?
Mixed - mostly serous
In regards to serous or mucous acini, what is the sublingual gland made up of?
Mixed - mostly mucous
Where are the majority of the minor salivary glands?
Palate
Minor gland of the tongue
Circumvallate papillae
–serous
Glands of Von ebner
Minor gland of the tongue
Anterior ventral
Mucous
Glands of Blandin and Nuhn
Minor gland of the tongue
Posterior lateral border
Mucous
Glands of Weber
Swelling due to ductal system being interrupted/ broken usually due to trauma
Mucocele
_____ is a mucocele of the sublingual gland that occurs above the mylohyoid muscle
ranula
_____ is a mucocele of the sublingual gland that occurs below the mylohyoid muscle
Plunging ranula
____;
Mucins get stuck in salivary duct and calcifies blocking the duct
Sialolith
\_\_\_\_ is an idiopathic and reactive pathology Occurs on palate Pseudoepitheliomatous hyperplasia Sialometaplasia Coagulative necrosis of the glands
Necrotizing sialometaplasia
Autoimmune disorder Dry mouth and dry eyes Primary vs. Secondary Bilateral enlargement of parotid gland Benign lymphoepithelial lesion (BLEL) Mikulicz’s disease Laboratory values Anti-SS-A Anti-SS-B RF ANA
Sjogren syndrome
Are diseases of parotid glands more often benign or malignant?
Even between the 2
Are diseases of submand glands more often benign or malignant?
Malignant
Are diseases of sublingual glands more often benign or malignant?
Mostly malignant
Are diseases of buccal mucosa more often benign or malignant?
Even
Are diseases of palate more often benign or malignant?
Even
Are diseases of upper lip more often benign or malignant?
Benign
Are diseases of lower lip more often benign or malignant?
Malignant
Are diseases of Tongue more often benign or malignant?
Malignant
Are diseases of retromolar pad more often benign or malignant?
Malignant
Are diseases of floor of mouth more often benign or malignant?
Malignant
The following are \_\_\_\_ salivary gland tumors: Benign Mixed Tumor (Pleomorphic Adenoma) Monomorphic Adenoma Warthin’s Tumor (Papillary Cystadenoma Lymphomatosum) Oncocytoma Ductal Papillomas
Benign Salivary Gland Tumor
Benign Salivary gland tumor Most common salivary gland neoplasm Middle-aged females Painless slowly growing mass Variable histology Mixture of ductal and myoepithelial elements Encapsulated
Pleomorphic adenoma
Benign Salivary gland tumor Upper lip Middle-aged females Painless slowly growing mass Uniform pattern Single layered cords of columnar or cuboidal epithelium May demonstrate papillary projections Loose connective tissue stroma, with prominent vascularity Thin fibrous capsule
Monomorphic adenoma
Benign Salivary gland tumor 2nd most common benign salivary gland neoplasm Parotid gland Bilateral Middle-aged males Lower in blacks Smoking Painless slowly growing nodular mass Oncocytic ductal epithelium Uniform double rows Lymphoid aggregate Papillary cystic configuration
PAPILLARY CYSTADENOMA LYMPHOMATOSUM
WARTHIN’S TUMOR
Benign Salivary gland tumor Rare salivary gland neoplasm Large epithelial cells, oncocytes Females, 8th decade Parotid Painless slowly growing mass Multifocal Large polyhedral cells abundant in granular eosinophilic cytoplasm mitochondria Limited stroma Thin fibrovascular septa Lymphoid infiltrate
Oncocytoma
The following are \_\_\_\_\_ Salivary gland tumors: Mucoepidermoid Carcinoma Adenoid Cystic Carcinoma Polymorphous Low-Grade Adenocarcinoma Acinic Cell Carcinoma Carcinoma ex-Mixed Tumor Adenocarcinoma NOS
Malignant
Malignant Salivary gland tumor Most common malignant salivary gland neoplasm Middle-aged females Clinically mistaken for a mucocele Mucous producing cells Epidermoid (squamous) cells May be cystic and / or solid
Mucoepidermoid Carcinoma
Malignant Salivary gland tumor Best recognized salivary gland tumor Middle-aged females Slowly growing mass, painful Myoepithelial and ductal cells Perineural and perivascular invasion Cribriform pattern SWISS CHEESE
Adenoid Cystic Carcinoma
Malignant Salivary gland tumor Common malignant MINOR salivary gland neoplasm Middle-aged females Favors palate Deceptive uniform appearance Different growth patterns Perineural and perivascular invasion Indian filing
Polymorphous Low-Grade Adenocarcinoma
Malignant Salivary gland tumor Parotid Serous acinar differentiation Middle-aged females Slow-growing Low-grade malignancy Well circumscribed May be infiltrative Serous acinar cell Abundant granular basophilic cytoplasm and a round, stained eccentric nucleus
Acinic Cell Carcinoma
Malignant Salivary gland tumor Long standing pleomorphic adenoma Older adults Rapid growth Pain and ulceration Typical benign mixed tumor Malignant degeneration Cellular pleomorphism Abnormal mitotic activity Capsular invasion
Carcinoma ex-Mixed Tumor
Malignant Salivary gland tumor
Uncommon salivary gland neoplasm
Middle-aged females
Variable histology
Adenocarcinoma NOS
If there is a malignancy on retromolar pad, it is likely what tumor?
Mucoepidermoid carcinoma
