2018 Old Test #2 Flashcards
(136 cards)
1
Q
Kaposi sarcoma caused by HIV
A
false
2
Q
Congenital is hereditary. Familial is at birth and not associated with genetics
A
both false
3
Q
Turners syndrome
A
XO
4
Q
XXY 47 chromosomes
A
Klinefelter
5
Q
Somatic, skips generations
A
Autosomal recessive
6
Q
Which of the following is not associated with neurofibromatosis
A
Intestinal polyposis
7
Q
What is vitamin D resistant rickets
A
x-linked
8
Q
MEN type II has thyroid cancer and oral mucosal nodules
A
both true
9
Q
The only that doesn’t present with facial asymmetry
A
Marie Santon disease
10
Q
Acromegaly
A
After the closure of epiphyseal plates
11
Q
Cleft lip results from
A
Failure of maxillary and medial nasal processes to fuse
12
Q
Macroglossia is caused by
A
Amyloidosis
13
Q
Branchial cleft cyst has similar histology to
A
Lymphoepithelial cyst
14
Q
Cystic hygroma is
A
Cluster of lymphatic vessels
15
Q
Cystic hygroma
A
Airway obstruction
16
Q
Fordyce granules
A
Ectopic sebaceous gland
17
Q
Port wine stain is associated with what cranial nerve
A
5- trigeminal
18
Q
Peutz Jegher presents with what
A
Perioral freckling
19
Q
Which of the following is not associated with neoplasm
A
Malignancy
20
Q
Which of the following most likely has head and neck cancer
A
No answer provided
21
Q
Abnormal cell growth that has not gone through Basement Membrane
A
dysplasia
22
Q
TF carcinomas metastasize via lymphatics. Sarcomas metastasize via lymphatics
A
true then false
23
Q
Barr body
A
Inactivated X chromosome
24
Q
What females have that protects them from x-linked diseases
A
Lyonization
25
Carcinoma is ectoderm. Sarcoma is mesoderm
both true
26
The most common soft tissue carcinoma of children
Rhabdomyosarcoma
27
Most of the malignancies in the US are accounted for by
None of the above - carcinoma
28
Which tumor has all three germ layers
teratoma
29
Grading done by pathologist, staging done by clinician
both true
30
you can diagnose SCC clinically
false
31
Determine survival of melanoma by
invasion
32
Which of the following is not a part of the ABCD
compressible
```
Correct:
Asym
Border irreg
Color
Diameter
```
33
The risk factor for lower lip vermillion carcinoma
Actinic radiation
34
Most common salivary lesion on the lower lip
Mucocele
35
SCC metastasizes to the regional lymph nodes
true
36
Philadelphia chromosome associated with
Chronic myelogenous leukemia
37
Tumor suppressor recessive, oncogene is dominant
both true
38
Tumor suppressor mutation is to have effect on cancer formation
loss of function
39
Uterine mass
Leiomyoma
40
Bilateral parotid enlargement, dry eyes and mouth
Sjogrens syndrome
41
Bilateral ulcers on the hard palate
Necrotizing sialometaplasia
42
Most common salivary gland neoplasm
Pleomorphic adenoma
43
Monomorphic adenoma
Most common on upper lip
44
Which of the following has male predisposition
Warthin’s tumor
45
The most common spot for the PLGA is
palate
46
Which presents with granulomatous inflammation
Crohn’s disease
47
Which is the most likely to metastasize
SCC
48
Lateral border of the tongue is high risk site for SCC
true
49
Which of the following is true about congestive heart failure
Right sided is caused by left sided
50
Barrett esophagus leads to
adenocarcinoma
51
Which of the following does not result from H pylori infection
SCC
52
Meckel Diverticulosis is in what organ
Small intestine
53
Carcinoid tumor releases what hormone
serotonin
54
Complete loss of blood supply that leads to necrosis
infarct
55
Which of the following does not result from myocardial infarction
angina
56
Which of the following is not commonly associated with fixed stenosis
necrosis
57
Which of the following is not a cause of MI
Aneurysm
58
Which of the following is the most common congenital heart defect
VSD
59
Which of the following is not true about infective endocarditis
Viral infection
60
Invagination of small intestine on itself
Intussusception
61
Chronic congestive liver disease is caused by
Right sided heart failure
62
Krukenberg tumor is found in
ovary
63
Which of the following is not a risk factor for atherosclerosis
aneurysm
64
Tumor suppressor genes act in a recessive manner. Oncogenes act in a dominant manner.
both true
65
Salivary tumor most likely to appear on UPPER LIP
monomorphic adenoma
66
Genotype is 45 X0
turner syndrome
67
Aortic dissection
Marfan syndrome
68
Woman has father with x-linked disease, lyonization is 50:50, what are the odds the child will have it
50
69
What are the chances a father with x-linked disease will pass to son
0
70
Looking at family tree, males and females equally effected, skips generations
auto recessive
71
Missense mutations
```
Substitution of one amino acid
Can have fatal effects
Can have no big deal effects
Causes sickle cell anemia
All of the above
```
```
Substitution of one amino acid
Can have fatal effects
Can have no big deal effects
Causes sickle cell anemia
All of the above
```
ALL ABOVE
72
Granulomatous inflammation occurs in
chrons
73
Crohn’s disease can present as
```
Oral lesions
Thickened intestinal wall
Fistula formation
Low malignancy
Occurs in distal ileum and colon
All of the above
```
all above
74
```
Ulcerative colitis can present as
Pseudopolyps
Thin intestinal wall
Increased risk of malignancy
All of the above
```
all above
75
Paramedial lip pits
Express saliva????
For sure this tho:
defective merging between mandibular processes
76
Lionization
Protects females by using other x chromosome
77
Which of the following is not associated with MEN 2B
pituitary tumor
78
Which of the following is not a sign of Neurofibromatosis
polyp
79
Peutz Jegher type of polyps
Hamartomatous polyps
80
What type of polyps in Gardner syndrome?
Adenomatouspolyps
81
Pt with downward slanting palpebral fissures, Colomba of lower eye lid, and hypoplastic zygoma
Mandibulofacial dysplasia (Treacher Collins)
82
Keloid is made of
collagen
83
Which of the following is due to a defect in fibrillin
marfan
84
Pt has cysts of the jaw and multiple early onset basal carcinomas
nevoid basal cell carcinoma
85
Which of the following expresses asymmetry
Parry Romberg
86
Peri-oral freckling occurs in what syndrome
Peutz-Jegher
87
Signs of Pierre Robin:
Mandibular hypoplasia
Palatal cleft
Glossoptosis
All of the above
ALL ABOVE
88
Macroglossia is caused by
amyloidosis
89
Cystic Hygroma involves what type of vessels?
lymph vessel
90
Carcinoid tumors secrete what hormone
serotonin
91
Sarcoma are more common in children and carcinoma is more common in old people
both true
92
Rhabdomyosarcoma is common in children and more common than Rhabdomyoma (benign)
both true
93
Sarcoma is from mesoderm and Carcinoma is from ecto/endoderm
both true
94
Krukenberg tumor is found in the
ovaries
95
Sarcomas travel by hematogenous route and end in the lungs. Carcinomas travel via lymphatics and end up in the lymph nodes
Both true
96
Most common tumor of the lungs?
mestastic
97
Which is the most common gene translocation for chronic myelogenous leukemia
t (9:22)
98
question about MEN 2A
false
99
High risk of cancer in all the following except
Acanthosis negricans
this is a paraneoplastic sympotom
100
Which has the Alpha 1-anti-trypsin deficiency
Panaciniar emphysema
101
Lower lip is special because you have
actinic radiatioin
102
Loss of sympathetic innervation causes all of following except (aka Horners)
Exophthalmia → should be enophthalmos
IDK what this means
103
Spilling mucin into surrounding tissue and forming granulation tissue
mucocele
104
H. Pylori can do all of the following except
does not lead to squamous cell carcinoma
does lead to Chronic gastritis
Peptic ulcer disease
Gastric adenocarcinoma
Gastric MALT
lymphoma
105
upper lip tunor
Monomorphic adenoma
106
Most common salivary gland tumor
Pleomorphic adenoma (mixed benign tumor)
107
Most common malignant salivary gland tumor
Mucoepidermoid carcinoma
108
Salivary gland tumor that favors the hard palate
Polymorphous low grade adenocarcinoma
109
Salivary gland tumor that appears blue
Mucoepidermoid carcinoma
110
Histologically looks like swiss cheese
Adenoid cystic carcinoma (poor long-term prognosis)
111
Histologically a mixture of ductal and myoepithelial elements
Pleomorphic adenoma
112
Histologically a uniform pattern
Monomorphic adenoma
113
Histologically similar to parotid
acinic cell carcinoma
114
Pseudoepitheliomatous hyperplasia (PEH)
Granular cell tumor
115
Which is not true of in-situ
Has invaded the basement membrane (in-situ has not yet invaded)
116
Which is the most likely to metastasize
squamous cell carcinoma
117
Which is not high risk for cancer?
dorsal tongue
118
90% of Erythroplakia will be dysplastic, 20% of Leukoplakia is dysplastic
both true
119
Surfactant is secreted by
type 2 pneuomcytes
120
Characteristics of dysplasia except:
Hyperkeratosis (this is answer)
(correct answer actually a characteristic) → dyskeratosis
121
What type of collapsed lung is caused by obstruction of the airway
Resorption
122
What type of collapsed lung is caused by fluid within pleural cavity
Compression
123
What type of collapsed lung is caused by local or generalized fibrotic changes
contraction
124
Melanoma prognosis is dependent on
depth
125
COPD
Chronic bronchitis and emphysema
126
Plummer Vincent is not
Pernicious anemia
but is → autoimmune atrophic gastritis
127
Under 1 cm is always benign, over 1 cm is malignant
both false
128
Increased risk of adenocarcinoma
barretts esophag
129
These are all sarcoma/mesoder except
myxoma
130
Meckel diverticulum is a developmental defect of
Small intestine (ileum)
131
Brachial cyst is histologically similar to
Cervical lymphoepithelial cyst
132
Alpha fetoprotein is a marker for
Hepatocellular carcinoma
133
f you think someone has blood under their skin, what is the technique, you use to blanch
diascope
134
Mesothelioma is a benign outgrowth of the pleura. It decreases with asbestos exposure
both false
correct would be malignant and increases
135
Most pain receptors are on
pleura of lungs
136
Pt has pheochromatoma of adrenal medulla, and nodules in mouth. What do they have?
Men IIb
