2018 Old Test #2 Flashcards
Kaposi sarcoma caused by HIV
false
Congenital is hereditary. Familial is at birth and not associated with genetics
both false
Turners syndrome
XO
XXY 47 chromosomes
Klinefelter
Somatic, skips generations
Autosomal recessive
Which of the following is not associated with neurofibromatosis
Intestinal polyposis
What is vitamin D resistant rickets
x-linked
MEN type II has thyroid cancer and oral mucosal nodules
both true
The only that doesn’t present with facial asymmetry
Marie Santon disease
Acromegaly
After the closure of epiphyseal plates
Cleft lip results from
Failure of maxillary and medial nasal processes to fuse
Macroglossia is caused by
Amyloidosis
Branchial cleft cyst has similar histology to
Lymphoepithelial cyst
Cystic hygroma is
Cluster of lymphatic vessels
Cystic hygroma
Airway obstruction
Fordyce granules
Ectopic sebaceous gland
Port wine stain is associated with what cranial nerve
5- trigeminal
Peutz Jegher presents with what
Perioral freckling
Which of the following is not associated with neoplasm
Malignancy
Which of the following most likely has head and neck cancer
No answer provided
Abnormal cell growth that has not gone through Basement Membrane
dysplasia
TF carcinomas metastasize via lymphatics. Sarcomas metastasize via lymphatics
true then false
Barr body
Inactivated X chromosome
What females have that protects them from x-linked diseases
Lyonization
Carcinoma is ectoderm. Sarcoma is mesoderm
both true
The most common soft tissue carcinoma of children
Rhabdomyosarcoma
Most of the malignancies in the US are accounted for by
None of the above - carcinoma
Which tumor has all three germ layers
teratoma
Grading done by pathologist, staging done by clinician
both true
you can diagnose SCC clinically
false
Determine survival of melanoma by
invasion
Which of the following is not a part of the ABCD
compressible
Correct: Asym Border irreg Color Diameter
The risk factor for lower lip vermillion carcinoma
Actinic radiation
Most common salivary lesion on the lower lip
Mucocele
SCC metastasizes to the regional lymph nodes
true
Philadelphia chromosome associated with
Chronic myelogenous leukemia
Tumor suppressor recessive, oncogene is dominant
both true
Tumor suppressor mutation is to have effect on cancer formation
loss of function
Uterine mass
Leiomyoma
Bilateral parotid enlargement, dry eyes and mouth
Sjogrens syndrome
Bilateral ulcers on the hard palate
Necrotizing sialometaplasia
Most common salivary gland neoplasm
Pleomorphic adenoma
Monomorphic adenoma
Most common on upper lip
Which of the following has male predisposition
Warthin’s tumor
The most common spot for the PLGA is
palate
Which presents with granulomatous inflammation
Crohn’s disease
Which is the most likely to metastasize
SCC
Lateral border of the tongue is high risk site for SCC
true
Which of the following is true about congestive heart failure
Right sided is caused by left sided
Barrett esophagus leads to
adenocarcinoma
Which of the following does not result from H pylori infection
SCC
Meckel Diverticulosis is in what organ
Small intestine
Carcinoid tumor releases what hormone
serotonin
Complete loss of blood supply that leads to necrosis
infarct
Which of the following does not result from myocardial infarction
angina
Which of the following is not commonly associated with fixed stenosis
necrosis
Which of the following is not a cause of MI
Aneurysm
Which of the following is the most common congenital heart defect
VSD
Which of the following is not true about infective endocarditis
Viral infection
Invagination of small intestine on itself
Intussusception
Chronic congestive liver disease is caused by
Right sided heart failure
Krukenberg tumor is found in
ovary
Which of the following is not a risk factor for atherosclerosis
aneurysm
Tumor suppressor genes act in a recessive manner. Oncogenes act in a dominant manner.
both true
Salivary tumor most likely to appear on UPPER LIP
monomorphic adenoma
Genotype is 45 X0
turner syndrome
Aortic dissection
Marfan syndrome
Woman has father with x-linked disease, lyonization is 50:50, what are the odds the child will have it
50
What are the chances a father with x-linked disease will pass to son
0
Looking at family tree, males and females equally effected, skips generations
auto recessive
Missense mutations
Substitution of one amino acid Can have fatal effects Can have no big deal effects Causes sickle cell anemia All of the above
Substitution of one amino acid Can have fatal effects Can have no big deal effects Causes sickle cell anemia All of the above
ALL ABOVE
Granulomatous inflammation occurs in
chrons
Crohn’s disease can present as
Oral lesions Thickened intestinal wall Fistula formation Low malignancy Occurs in distal ileum and colon All of the above
all above
Ulcerative colitis can present as Pseudopolyps Thin intestinal wall Increased risk of malignancy All of the above
all above
Paramedial lip pits
Express saliva????
For sure this tho:
defective merging between mandibular processes
Lionization
Protects females by using other x chromosome
Which of the following is not associated with MEN 2B
pituitary tumor
Which of the following is not a sign of Neurofibromatosis
polyp
Peutz Jegher type of polyps
Hamartomatous polyps
What type of polyps in Gardner syndrome?
Adenomatouspolyps
Pt with downward slanting palpebral fissures, Colomba of lower eye lid, and hypoplastic zygoma
Mandibulofacial dysplasia (Treacher Collins)
Keloid is made of
collagen
Which of the following is due to a defect in fibrillin
marfan
Pt has cysts of the jaw and multiple early onset basal carcinomas
nevoid basal cell carcinoma
Which of the following expresses asymmetry
Parry Romberg
Peri-oral freckling occurs in what syndrome
Peutz-Jegher
Signs of Pierre Robin:
Mandibular hypoplasia
Palatal cleft
Glossoptosis
All of the above
ALL ABOVE
Macroglossia is caused by
amyloidosis
Cystic Hygroma involves what type of vessels?
lymph vessel
Carcinoid tumors secrete what hormone
serotonin
Sarcoma are more common in children and carcinoma is more common in old people
both true
Rhabdomyosarcoma is common in children and more common than Rhabdomyoma (benign)
both true
Sarcoma is from mesoderm and Carcinoma is from ecto/endoderm
both true
Krukenberg tumor is found in the
ovaries
Sarcomas travel by hematogenous route and end in the lungs. Carcinomas travel via lymphatics and end up in the lymph nodes
Both true
Most common tumor of the lungs?
mestastic
Which is the most common gene translocation for chronic myelogenous leukemia
t (9:22)
question about MEN 2A
false
High risk of cancer in all the following except
Acanthosis negricans
this is a paraneoplastic sympotom
Which has the Alpha 1-anti-trypsin deficiency
Panaciniar emphysema
Lower lip is special because you have
actinic radiatioin
Loss of sympathetic innervation causes all of following except (aka Horners)
Exophthalmia → should be enophthalmos
IDK what this means
Spilling mucin into surrounding tissue and forming granulation tissue
mucocele
H. Pylori can do all of the following except
does not lead to squamous cell carcinoma
does lead to Chronic gastritis
Peptic ulcer disease
Gastric adenocarcinoma
Gastric MALT
lymphoma
upper lip tunor
Monomorphic adenoma
Most common salivary gland tumor
Pleomorphic adenoma (mixed benign tumor)
Most common malignant salivary gland tumor
Mucoepidermoid carcinoma
Salivary gland tumor that favors the hard palate
Polymorphous low grade adenocarcinoma
Salivary gland tumor that appears blue
Mucoepidermoid carcinoma
Histologically looks like swiss cheese
Adenoid cystic carcinoma (poor long-term prognosis)
Histologically a mixture of ductal and myoepithelial elements
Pleomorphic adenoma
Histologically a uniform pattern
Monomorphic adenoma
Histologically similar to parotid
acinic cell carcinoma
Pseudoepitheliomatous hyperplasia (PEH)
Granular cell tumor
Which is not true of in-situ
Has invaded the basement membrane (in-situ has not yet invaded)
Which is the most likely to metastasize
squamous cell carcinoma
Which is not high risk for cancer?
dorsal tongue
90% of Erythroplakia will be dysplastic, 20% of Leukoplakia is dysplastic
both true
Surfactant is secreted by
type 2 pneuomcytes
Characteristics of dysplasia except:
Hyperkeratosis (this is answer)
(correct answer actually a characteristic) → dyskeratosis
What type of collapsed lung is caused by obstruction of the airway
Resorption
What type of collapsed lung is caused by fluid within pleural cavity
Compression
What type of collapsed lung is caused by local or generalized fibrotic changes
contraction
Melanoma prognosis is dependent on
depth
COPD
Chronic bronchitis and emphysema
Plummer Vincent is not
Pernicious anemia
but is → autoimmune atrophic gastritis
Under 1 cm is always benign, over 1 cm is malignant
both false
Increased risk of adenocarcinoma
barretts esophag
These are all sarcoma/mesoder except
myxoma
Meckel diverticulum is a developmental defect of
Small intestine (ileum)
Brachial cyst is histologically similar to
Cervical lymphoepithelial cyst
Alpha fetoprotein is a marker for
Hepatocellular carcinoma
f you think someone has blood under their skin, what is the technique, you use to blanch
diascope
Mesothelioma is a benign outgrowth of the pleura. It decreases with asbestos exposure
both false
correct would be malignant and increases
Most pain receptors are on
pleura of lungs
Pt has pheochromatoma of adrenal medulla, and nodules in mouth. What do they have?
Men IIb
