Special Method: Assay of Alkaloids & Amines

Question 1

Alkaloids

Answer 1

Obtained from plants, animals, or synthetic sources
Contain organic nitrogen
Amine
Possesss physiological activity

Question 2

Assay of Alkaloidal Drugs and preparations

Answer 2

For Standardization
Proof of Purity
Commerical evaluation
Pharmacolegal purposes

Question 3

Methods of quantitative estimation of alkaloids

Answer 3

Volumetric
Gravimetric
Spectrophotometric
Electrometric
Physiological

Question 4

Methods of separation

Answer 4

use of immiscible solvents such as Ether, water-chloroform, water-ether
Extractives are combined, evaporated to dryness and weighed
Dissolved in an excess acid of known normality and the excess of acid determined by titration with a standard solution of alkali

Question 5

Indicator used in Assay of alkaloids and amines

Answer 5

Methyl Red

Question 6

TOTAL amount of class/group of plant principles

Answer 6

Proximate Analysis

Question 7

Total amount of specific, single compound/chemical species

Question 7

Total amount of specific, single compound/chemical species

Answer 7

Ultimate Assay

Question 8

Total Alkaloid content of Alkaloids or Glycosides

Answer 8

Proximate assay

Question 9

Atropine or Morphine Content

Answer 9

Ultimate Assay