Qualitative-Quantitative Chemistry Flashcards

1
Q

Qualitative-Quantitative Chemistry

A

Analytical Chemistry
Pharmaceutical Chemistry

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2
Q

Branch of chemistry which provides information relative to the composition of matter

A

Qualitative-Quantitative Chemistry

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3
Q

Test for the nature of the consitituents of a given material composition determination

A

Qualitative Chemistry

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4
Q

Qualitative Chemistry

A

Identification of contents in a given sample
Quality or character of chemical
Composition determination of chemical
Ascertainment of impurities present in a given sample
Answers the question: What is present in a given sample?

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5
Q

Focuses on the proportion of a certaing component in a sample

A

Quantitative Chemistry

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6
Q

Determination of elements, species, or compounds present in a sample

A

Quantitative Chemistry

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7
Q

Answers the quesntion: How much is present in the sample

A

Quantitative Chemistry

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8
Q

Application of Quantitative Chemistry

A

Analysis and determination of:
- Purity and quality of drugs and chemicals
- Chemical constituents in the human body, serves as a diagnostic aids during disease
- Medicinal agents and their metabolites

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9
Q

Determination of presence and amount of substance, purity, strength, and potency of a drug

A

Pharmaceutical Assay

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10
Q

Tests to identify that a particular substance is the medicine that it claims to be

A

Identification test

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11
Q

Tetsing methods and acceptable ranges for the potency of a medicine

A

Strength

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12
Q

Information on impurities that may be present in a medicine and the amounts of these taht are permitted, along with testing methods to identify and measure them

A

Purity

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13
Q

Any component in the API or finished dosage form which is not the desired porduct of other formulation components

A

Impurities

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14
Q

Laboratory Test to predict and demonstarte how a medicine will be released as it enters the human body

A

Performance

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15
Q

Classification of Analysis

A

Based on
Size of the sample
Nature of Method
Percent Extractive

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16
Q

Based on the size of the sample

A

Macroanalysis
Semi-macroanalysis
Microanalysis
Ultramicroanalysys
Trace Analysis

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17
Q

Macroanalysis

18
Q

Semi macroanalysis

19
Q

Microanalysis

20
Q

Ultramicroanalysis

21
Q

Trace Analysis

A

100-10,000ppm

22
Q

Based on the Nature of Method

A

Chemical Method/Classical Method
Physico-chemical Method/Instrumental method
Biological Methods
Special Methods

23
Q

Determination of the VOLUME of a solution of KNOWN concentration required to react with a given amount of the substance being analyzed

A

Volumetric Methods

24
Q

Analysis of weight, process of SEPARATION and WEIGHING the compound of known composition

A

Gravimetric Methods

25
Selective separation of the analyte bye precipitation, followed by the very non-selective measurement of mass
Gravimetric Method
26
Measurement of the volume of a gas liberated or of decrease in volume of a gas when a suitable reagent is used to remove one of the gases present
Gasometric Methods
27
Chemical/Classical methods
Volumetric Gravimetric Gasometric
28
Physicochemical Methods
Optical Methods Electrochemical Methods Chromatographic Methods
29
Optical Methods
Refractometry Polarimetry Spectrophotometry
30
Bending / Refraction of Light
Refractometry
31
Rotation of plane polarized light
Polarimetry/Rotary Power
32
Measurement on spectra and power of absorbed transmitted, reflected, or emitted energy
Spectrophotometry
33
Electrochemical Methods
Potentiometry Polarography
34
Measurement of electrode/electric potential (pH determination)
Potentiometry
35
Measurement of electric current
Polarography
36
A solution of a mixture containing inert materials, drug principles, and impurities is separated into its components while moving through a bed of fixed porous solid having different and reversible affinity for the substances being separated.
Chromatographic Methods
37
Quantitative assay of drugs using intact animals, animal prep, isolated living tissues, and cells or microorganisms
Biological Methods
38
Measurement of the relative potency or activity of compounds by determining the amount required to reduce a specific, defined effect on a suitable test animals or organ under standard conditions
Biological assay
39
Biological assay performed with the microorganism, such as bacteria, fungi, and yeast
Microbial Assay
40
Analysis of crude drugs and derived plant products
Special assay
41
Total class of plant principles
Proximate Assay
42
Single Chemical species
Ultimate Assay