SOS response Flashcards
1
Q
when is SOS response activated
A
if DNA is heavily damaged by mutagenic agents
2
Q
SOS response involves what
A
Recombination, repair and replication
3
Q
what polymerase replicates DNA in damaged regions
A
V but cannot be replicated accurately
4
Q
SOS response does what overall
A
eliminates gaps but increases the frequency of replication errors
5
Q
In the absence of DNA damage, what happens (lexA)
A
LexA binds to DNA regions that regulate transcription of SOS response genes and keeps their expression levels low
6
Q
When their is DNA damage, what happens (RecA)
A
RecA binds to single stranded regions of damaged DNA
7
Q
RecA does what in terms of LecA
A
stimulates LexA to inactivate itself as LexA controls SOS expression
