mRNA splicing

Question 1

What are exits

Answer 1

Expressed sequences however not ALWAYS

Question 2

What is the splicesome made of and what does it do

Answer 2

Made of Ribo proteins and small RNAs, removes introns

Question 3

Alternative splicing leads to what

Answer 3

Single gene can encode more than one kind of polypeptide

Question 4

What is exon shuffling

Answer 4

Introns increase the probability of crossing over between the exons alleles of a gene

Question 5

Release of introns from splicesome leads to what

Answer 5

Degradation

Question 6

Small RNAs help do what

Answer 6

Catalyse

Question 7

What are ribozymes

Answer 7

RNA molecules that function as enzymes

Question 8

What caps are given to the 5’ and 3’ ends

Answer 8

5’ - 5’ cap end made of Guanine

3’ - Poly A tail made of 50-250 adenine Nucelotides

Question 9

What is the purpose of the caps (3)

Answer 9

1) promote export of mRNA from nucleus 2) facilitate ribosome attachment for translation 3) protect mRNA from degradation

Question 10

What are introns

Answer 10

Intervening sequences