Postrep repair Flashcards

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1
Q

Thymine dimer in template strand blocks what

A

DNA polymerase III progress ie replication

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2
Q

DNA polymerase III does what first

A

restarts DNA synthesis past the dimer, leaving a gap in the nascent strand

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3
Q

what protein is needed

A

RecA

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4
Q

RecA does what

A

recombinaton

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5
Q

RecA binds to what

A

to the single strand DNA at the gap and mediates base pairing with the homologous segment of the sister double helix to fill the gap

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6
Q

DNA polymerase then does what and ligase

A

Polymerase fills the gap in the sister double helic and DNA ligase seals the nick

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