Mutation

Question 1

what is transition

Answer 1

replaces like with like

Question 2

What is transversion

Answer 2

replaces opposites

Question 3

What are simple tandem repeats

Answer 3

repeated sequence of one to six nucleotide pairs

Question 4

what is a trinucleotide repeat

Answer 4

repeats of 3 nucleotide pairs

Question 5

what is anticipation

Answer 5

the increased severity of disease or earlier age of onset in successive generations as the trinucleotide copy number increases

Question 6

anticipation usually occurs during what

Answer 6

DNA replication

Question 7

describe how a trinucleotide can be repeated during DNA replication

Answer 7

A hairpin can form on the newly synthesised strand

Question 8

Name the 5 DNA repair mechanisms in EColi

Answer 8

Light-dependent repair (photoreactivation)
Excision repair
Mismatch repair
Postreplication repair
Error-prone repair system (SOS response)

Question 9

When is light dependant repair used

Answer 9

when dna is exposed to UV

Question 10

Photoreactivation is performed by what enzyme

Answer 10

Photolyase

Question 11

DNA exposed to UV forms what

Answer 11

T dimers

Question 12

What DNA enzyme binds to the T dimers

Answer 12

Photolyase

Question 13

DNA photolyase activated by what

Answer 13

blue light

Question 14

DNA photolyase does what

Answer 14

Cleaves T Dimers