Sos- Cerebral Neoplasias Flashcards

1
Q

tumor location

A

meningioma

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2
Q

tumor location

A

astrocytomas
oligodendroglioma
ganglioglioma

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3
Q

metastatic tumor location

A

anywhere

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4
Q

tumor location
crosses corpus callosum

A

glioblastoma
lymphoma

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5
Q

tumor location

A

ependymoma
central neurocytoma
colloid cyst

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6
Q

tumor location

A

pituitary adenoma
craniopharyngioma

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7
Q

tumor location

A

medulloblastoma
ependymoma
pilocytic astrocytoma
hemangioblastoma

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8
Q
A

metastatic neoplasms

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9
Q

what kind of metastatic neoplasm

A

melanoma

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10
Q

metastatic hemorrhagic neoplasms

A

lung
kidney
melanoma
choriocarcinoma

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11
Q

location?

A

gray-white matter junction

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12
Q

2 types of infiltrating gliomas

A

astrocytoma
oligodendroglioma

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13
Q

non-infiltrating glioma

A

gangliomas

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14
Q

chaotic gray matter

A

metastatic neoplasm

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15
Q
A

metastatic neoplasm

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16
Q

HMG-45

A

melanoma stain

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17
Q
A

metastatic neoplasm

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18
Q
A

metastatic brain cancer

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19
Q
A

metastatic brain cancer

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20
Q

astrocytoma
oligodendroglioma

A

infiltrative lesions

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21
Q

Arise from neoplastic astrocytes and oligodendrocytes within the white matter and infiltrate into gray matter

A

infiltrative gliomas

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22
Q

In children, where are the most common locations of infiltrative gliomas

A

brain stem or thalamus

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23
Q

stain for astrocytomas

A

GFAP+

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24
Q

infiltrating gliomas

A

astrocytomas
oligodendrogliomas

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25
Q

GFAP+

A

astrocytes

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26
Q

what glial cell attaches to neurons and blood vessels

A

astrocytes

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27
Q

normal or glioma

A

normal

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28
Q

GFAP+

A

astrocytoma

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29
Q

normal or glioma

A

glioma

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30
Q

WHO grade II
pleomorphic astrocytes

A

Astrocytoma

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31
Q

WHO grade III
pleomorphic astrocytes
mitoses (just 1)

A

anaplastic astrocytoma

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32
Q

WHO grade IV
pleomorphic astrocytes
mitoses
necrosis and/or microvascular proliferation

A

glioblastoma multiforme (GBM)

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33
Q

in white matter of young adults (30-40 yrs)
>10 yrs of survival

A

astrocytoma WHO grade II

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34
Q

infiltrating pleomorphic cells with increased cellularity

A

diffuse astrocytoma WHO grade II

35
Q

normal or neoplastic

A

normal

36
Q

neoplastic or normal
pale=edema

A

grade II astrocytoma

37
Q

adult 50 yrs
2-4 yr survival

A

who grade III
anaplastic astrocytoma

38
Q

1 mitotic feature
grade III what

A

anaplastic astrocytoma

39
Q

normal or neoplastic

A

neoplastic grade III

40
Q

50-60 yrs
irregular ring enhancing
1 yr survival

A

WHO grade IV
glioblastoma multiforme

41
Q

“butterfly lesion”

A

glioblastoma multiforme
WHO grade IV

42
Q

mitotic activity,
endothelial vascular proliferation
and necrosis

A

glioblastoma multiforme

43
Q

mitotic activity,
endothelial vascular proliferation
and necrosis

A

glioblastoma multiforme

44
Q

pseudopalasading necrosis (neoplastic cells around vessel)

A

glioblastoma multiforme

45
Q

necrosis w/ neoplastic cells around
KNOW THIS

A

glioblastoma multiforme (GBM)

46
Q

women>men
characteristic loss of chromosomes 1p, 19q

A

oligodendroglioma

47
Q

oligodendroglioma has characteristic loss of chromosomes ______

A

1p, 19q

48
Q

“fried egg” appearance

A

oligodendroglioma

49
Q

Perinuclear halos or fried egg appearance
Delicate capillaries
Calcification

A

oligodendroglioma

50
Q

infiltrates the corpus callosum
B-cell type

A

lymphoma

51
Q

explosion of lymphocytes

A

lymphoma

52
Q
A

lymphoma

53
Q

out of the two neoplasms that cross corpus callosum, which one has best prognosis

A

lymphoma

53
Q

3 periventricular neoplasms

A

ependymomas
central neurocytomas
colloid cyst

53
Q

pt comes in with vision problems
(ACTH, GH, or prolactin producing)

A

anterior pituitary adenomas

54
Q
A

pituitary adenoma (GH producing)

55
Q
A

pituitary adenoma (ACTH producing)

56
Q

oligomenorrhea
amenorrhea
galactorrhea

A

pituitary adenoma (prolactinoma)

57
Q
A

normal pituitary gland

58
Q

more acidophils

A

GH adenoma

59
Q

more basophils

A

ACTH adenoma

60
Q

hemorrhage in pituitary adenoma

A

pituitary apoplexy

61
Q

Rare benign tumors derived from embryonic pituitary tissue
(HAs, vomiting, vision loss, polyuria)

A

Craniopharyngioma

62
Q

calcification

A

Craniopharyngioma

63
Q

calcification

A

Craniopharyngioma

64
Q

Leftover from developing pituitary area: Rathkes pouch (in b/t anterior and posterior pituitary)

A

Rathke’s cleft cyst

65
Q

Mom presents to your pediatric clinic with her 5-year-old child and a chief complaint of her child awakes from sleep with a headache that improves during the day, and vomiting

A

choroid plexus papilloma
(see hydrocephalus and enlarged ventricles)

66
Q

rare benign _______tumor

A

choroid plexus

67
Q

papillary structures in CSF, what to think

A

choroid plexus

68
Q

You examine the brain of a 20-year-old man who was in a MVA
He had a recent history of fainting with a quick recovery

A

colloid cyst in foramen of monro

69
Q

colloid cyst
what kills the pt

A

blood from MVA into ventricular space

70
Q

Rare benign epidermal cyst arising from the third ventricle near the interventricular foramen
Can cause acute obstruction of CSF flow “drop attacks’ can be fatal

A

colloid cyst

71
Q

“drop attacks”

A

colloid cyst

72
Q

children
astrocytes
rare

A

pilocytic astrocytoma of optic n.

73
Q

pilocytic astrocytoma of optic nerve is associated w/ what

A

neurofibromatosis type I

74
Q

child
4th ventricle
ventricle enlargement
crying, wide gait

A

pilocytic astrocytoma

75
Q

dilated astrocystic processes

A

Rosenthal fibers

76
Q

most common low grade/benign glial tumor in children (see Rosenthal fibers)

A

Pilocytic Astrocytoma

77
Q

most common high grade/malignant pediatric CNS neoplasm

A

medulloblastoma

78
Q

(3rd ventricle huge and dark and dilated)
child

A

medulloblastoma

79
Q

homer-wright rosettes
neuroblastoma in the brain

A

medulloblastoma

80
Q

homer wright rosettes
synaptophysin +, chromogranin +

A

medulloblastoma

81
Q

found only in ventricles
synaptophysin and chromogranin +
(similar to oligo, but this one is a neuron) “fried egg”

A

central neurocytoma

82
Q

difference b/t oligodendroglioma and central neurocytoma

A

neurocytoma found in ventricles
oligodendroglioma found in neocortex

neurocytoma made from neurons
oligodendroglioma form oligodendocytes