Pavlick- Somatosensory Pathways Flashcards

1
Q

Afferent information transmitted by peripheral receptors

A

somatosensation

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2
Q

where is somatosensory cortex

A

post-central gyrus

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3
Q

1st order neuron cell body is where

A

dorsal root ganglion

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4
Q

2nd order neurons found where

A

dorsal horn of spinal cord

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5
Q

what neurons will decussate

A

2nd order

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6
Q

3rd order neurons found where

A

thalamus (and travel to sensory cortex)

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7
Q

______ order neuron that conveys environmental stimulus
Cell body lies in dorsal root ganglion

A

first order

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8
Q

peripheral sensory receptor that senses vibration

A

pacinian corpuscle (looks like cut onion on histology)

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9
Q

peripheral sensory receptor that senses skin stretch

A

Ruffini ending

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10
Q

peripheral sensory receptor that senses nociception

A

free nerve ending

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11
Q

peripheral sensory receptor that senses movement across skin (slippage)

A

Meissner’s corpuscle

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12
Q

peripheral sensory receptor that senses light pressure, edges (reading brail)

A

Merkel disc

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13
Q

peripheral sensory receptor that senses tension

A

golgi tendon organ

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14
Q

peripheral sensory receptor that senses changes in muscle length and rate of length change

A

muscle spindle

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15
Q

this somatosensory pathway focuses on proprioception, vibration, and 2-point discrimination

A

Dorsal Column Medial Lemniscus

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16
Q

this somatosensory pathway focuses on, temperature, nociception, crude touch

A

Anterolateral system (spinothalamic)

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17
Q

this somatosensory pathway focuses on unconscious proprioception and balance

A

spinocerebellar

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18
Q

stimulus from tissue damage that the brain may interpret as pain

A

nociception

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19
Q

first order neuron in DCML pathway that senses discriminative touch, vibration, and proprioception

A

dorsal column

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20
Q

second motor neuron in DCML that ascend and synapse in thalamus (VPL)

A

medial lemniscus

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21
Q

3rd order neurons synapse where

A

synapse in primary sensory cortex (parietal lobe) and project to 4th order neurons

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22
Q

2nd order neurons ascend to thalamus how

A

ipsilaterally

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23
Q

above T6, first order neurons ascend and synapse where

A

at cuneate fasciculus of dorsal horn

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24
Q

below T6, first order neurons ascend and synapse where

A

gracile fasciculus in dorsal horn

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25
below T6, DCML sensory info for a lot of the _______extremities
lower
26
_____ fasciculus deals with upper extremity sensations
cuneate
27
1st order neurons synapse on 2nd order neurons in
dorsal horn
28
decussate and ascend contralaterally as medial lemniscus and synapse on 3rd order neurons in VPL of thalamus
2nd order neurons
29
incomplete spinal cord injury affecting the dorsal columns
posterior cord syndrome
30
main causes of this include: B12 deficiency and neurosyphilis (tabes dorsalis)
posterior cord syndrome
31
sensory ataxia due to decreased proprioceptive input Decreased sensation of vibration and fine touch
posterior cord syndrome
32
Posterior cord syndrome as a result of neurosyphilis
tabes dorsalis
33
Responsible for transmitting proprioceptive information (unconscious)
Spinocerebellar pathway
34
1st order neuron in DRG enter dorsal horn of spinal cord and synapse onto 2nd order neurons in _________ (spinocerebellar tract)
nucleus dorsalis
35
2nd order neurons ascend to enter cerebellum through ______ (spinocerebellar tract)
cerebellar peduncles
36
Responsible for transmitting nociception, temperature, and crude touch, pressure
spinothalamic tracts
37
1st order neurons in DRG enter dorsal horn of spinal cord, synapses with 2nd order neuron in ______ (spinothalamic tract)
substantia gelatinosa
38
Decussates within 1-2 levels through _______ to ascend contralaterally (spinothalamic tracts)
anterior white commissure
39
2nd order neurons synapse on 3rd order neurons in __________ of thalamus (spinothalamic)
VPL
40
3rd order neurons projects to 4th order neurons in ________ (spinothalamic)
primary sensory cortex
41
Fluid-filled cyst forms within central canal and compromises anterior white commissure
Syringomyelia (central cord syndrome)
42
“cape_” distribution of sensory loss
central cord syndrome
43
What is in anterior white commissure?
axons of spinothalamic tract
44
Lesion above motor decussation will present with motor deficits _______ to lesion
contralateral
45
lesion below decussation will present with deficits _________________ to lesion
ipsilateral
46
lesion above sensory decussation will result in deficit________ to lesion
contralateral
47
lesion below sensory decussation will result in deficit________ to lesion
ipsilateral
48
blue red and what location is this
DCML--blue anterolateral system--red spinal cord
49
where
caudal medulla decussation of DCML tract
50
what is in the blue "man standing on the pyramid"
medial lemniscus (2nd order neuron of DCML)
51
location
medulla
52
"walrus" blue
pons medial lemniscus
53
where "sitting frog with mustache"
caudal midbrain
54
"upsidedown girl with a fro"
rostral midbrain (front of midbrain)
55
when 2nd order neurons (medial lemniscus) synapse where, they become 3rd order
VPL of thalamus
56
Midbrain structure which sends descending projections important for pain modulation
Periaqueductal Gray
57
Surrounding the cerebral aqueduct important for pain modulation
Periaqueductal Gray
58
As afferent pain signals ascend, collateral axons synapse with PAG to activate release of pain modulating products _________
serotonin NE endogenous opiate peptides (internal pain killers)
59
where can pain be interrupted (gate theory of pain)
substantia gelatinosa of anterior white commissure
60
______can stimulate an interneuron to actually block pain signal from spinothalamic fibers (b/c faster signals than spinothalamic-----due to A-delta and C fibers)
DCML fibers
61
pressure from "Livia" attempts to do what for menstrual cramps w/ a different, faster stimulus from separate pathway (DCML)
override pain signals (block them)
62
f
63
hemisection of spinal cord
Brown-Sequard Syndrome
64
loss of contralateral pain/temperature loss of ipsilateral vibration and/or proprioception below level of lesion loss of ipsilateral motor function below level of lesion
Brown-Sequard Syndrome