somatosensory II Flashcards

1
Q

spinothalamic tract projects to

A

VPL and intralaminar nuclei of thalamus

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2
Q

spinomesencephalic tract projects to

A

periaquaductal gray and tectum

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3
Q

spinoreticular tract projects to

A

reticular formation of medulla, pons, midbrain

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4
Q

spinobulbar tract projects to

A

brainstem nuclei

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5
Q

spinohypothalamic tract projects to

A

hypothalamus

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6
Q

allodynia

A

body says “turn down for what?!”

this is CENTRAL SENSITIZATION so where normal sensory information (like touch) can be percieved as pain.

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7
Q

sensory neurons enter the dorsal roots and bifurcate.
whats medial?
whats lateral?

A

medials are more MEATY (large fibers); synapse on lamina III-V
laterals are small fibers; synapse on lamina I, II, V

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8
Q

senses in ALS that are different from PCML system

A

hypesthesia, paresthesia, anesthesia

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9
Q

feel the burn: (pain and temp)
what are the fast burners? why?
lamina?

A

A delta are lightly myelinated

1 and 5

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10
Q

feel the burn: (pain and temp)
what are the slow burners? why?
lamina?

A

C are unmyelinated

1 and 2 and 3 (specific tracts in ALS have different lamina for C fibers)

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11
Q

lamina 2/3 is responsible for

A

cock-blocking the incoming pain signal.
SUBSTANTIA GELATINOSA it is the gate keeper for which signals are painful. pain is modulated at the level of the dorsal horn

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12
Q

lamina of nucleus proprius

A

4,5,6

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13
Q

what is a triple response to pain

A

you get fast pain sensation(A delta). slow pain sensation(C fibers), and inflammation

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14
Q

what is the role of hypothalamus in pain

A

connects the pain to emotion and ALS

=> this is is why people like S&M

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15
Q

what is the role of the insular cortex in pain

A

connections give you the “dislike” part of feeling pain

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16
Q

what is the role of the hippocapus in pain? amygdala?

A

hippocampus does pain memory

amygdala does the fear and anxiety part of pain

17
Q

you get stuck by a needle. what is the role of substance P in pain

A

1 - substance P (a peptide) is in nerves
2 - it is released at the site to bind with arterioles leading to the FLARE RESPONSE
3 - it binds to mast cells for inflammation/histamine - WHEAL RESPONSE

18
Q

what neurons DESCEND and synapse on lamina 2/3? why?

A

RAPHESPINAL pain modulation!

remember?! thats what happens in those two lamina!!

19
Q

I sprayed you with pepper spray.
what system is it?
fibers?
synapse?

A

paleospinothalamic tract
C fibers
lamina II and III

20
Q
you accidentally got warming lube on your face
what system is it?
first order neurons?
second order neurons?
decussate?
A

anterior trigeminothalamic tract is most important
1 = trigeminal ganglion
2 = spinal trigeminal nucleus
decussate to form the ventral trigeminothalamic tract

21
Q

what are the cock-blocker cells of the dorsal horn?

A

enkephalinergic interneurons. they work PRE-synaptically.

22
Q

opiates are also cock-blockers. How?

A

made in the PAG, they “go down” on the raphe nucleus so that when the pain signal comes in, it gets turned off

23
Q

serotonin is a ____

A

cock-blocker. but its for the primary aferents. aka the pain signal gets to the spinal cord, but serotonin kills the mood

24
Q

trans cutaneous nerve stimulation treatment is based off of

A

gate control theory

25
Q

rhizotomy is

A

transection of dorsal roots

26
Q

ventral trigeminothalamic tract mediates?

A

pain and temp sensation from the face and oral cavity

27
Q

dorsal trigeminothalamic tract mediates?

A

tactile discrimination and pressure sensation from the face and oral cavity (meissner/pacinian corpuscles)

28
Q

afferent/efferent limb of corneal reflex

A
ophthalmic n (V1)
facial n
29
Q

afferent/efferent limb jaw jerk reflex

A
mandibular n (V3)
mandibular n (V3)
30
Q

afferent/efferent limb tearing (lacrimal) reflex

A
ophthalmic n (V1)
facial n
31
Q

afferent/efferent limb oculocardiac reflex

A
ophthalmic n (V1)
vagal n