Solids and solution size Flashcards
1
Q
Crystalline
Polymorphs
A
Different type or formation of crystalline structure (stability so ability to dissolve)
2
Q
Crystalline
Co-crystals
A
Single phase materials composed of two or more different molecular or ionic compounds
3
Q
Amorphous
A
No structure to the arrangement of its structure
Glass is amorphous disorder in the molecules
4
Q
Triple point
A
- Exists as all three states
- Critical point combination of gas and liquid together
5
Q
Solution
A
Mixture of 2 or more components that forms a single phase at a homogenous to molecular level
6
Q
Solvent
A
- The component which determines the phase syrup bp water is solvent determines the phase
7
Q
Solute
A
- The other component which are dispersed as molecules or ions through solvent (in solution)
8
Q
Dissolution
A
Solid molecules move to solution form
9
Q
Solution vs Pharmaceutical Particles
A
- Single phase solution cannot be seen by magnifying
- Eventually equilibrium has been reached no more solute can be dissolved ‘saturated solution’
Heat from suspension to solution
10
Q
Solid in liquid
A
- Solutions of non-electrolyte
- Solubility of weak acid and weak bases
11
Q
Liquid in liquid
A
- Miscible liquid ethanol in water one dissolves completely in the other
- Partially miscibility is effected by temperature use separating funnel determined by concentration
12
Q
Gas in liquid
A
- Solubility of gas determined by temperature & pressure
- Decrease of solubility if temp rises
Water for injections in BP & chromatography HPLC