Smooth Muscle Contraction Flashcards

1
Q

Where is smooth muscle found

A

In walls of organs such as liver,intestines,pancreas

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2
Q

Anatomy of smooth muscle

A

-single nucleated
-fat in the middle skinny sat the end
-non striated
-function dependent

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3
Q

Smooth muscle cells

A

Spindle shaped (fusiform) and contain just one,
centrally located nucleus per cell
Not striated (hence “smooth”)
A lot found in GI tract (circular muscles) Mesh together

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4
Q

Smooth muscle contraction

A

Search uo

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5
Q

Excitation-contraction coupling

A

Search up

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6
Q

What are skeletal muscles stimulated by

A

Solely electrical stimulation

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7
Q

What are smooth muscle sarcomere are bordered by

A

Dense bodies

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8
Q

Cross bridge activation in smooth muscle

A

-calcium enters and binds to calmopdulin
-calciumcalmodulin bind to myosin light chain kinase
Atp is hydrolysed and phosphate is released

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9
Q

What filaments does smooth muscle contains

A

Actin and myosin just like skeletal and cardiac muscle

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10
Q

What parts does smooth muscle has

A

No troponin,calmodulin and myosin light chain kinase

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11
Q

What are the sources of calcium in smooth muscle

A

SR and extracellular

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12
Q

Smooth muscle contraction

A

,

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13
Q

Single unit smooth muscles

A

 Whole muscle responds as a single unit  Numerous gap junctions
 Can be innervated by:
 Nerves and hormones
 Spontaneous electrical activity  Local factors
 Examples
 Intestinal tract, uterus, small blood vessels

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14
Q

Multi-unit

A

 Whole muscle responds in individual units
 Few gap junctions
 Can be innervated by:
 Nerves and hormones
 Examples
 Large diameter blood vessels

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15
Q

What type of smooth muscle do air ways contain

A

Multi-unit smooth muscle

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16
Q

Dense bodies

A

Actin and myosin

17
Q

Gap junctions

A

Excitation-Contraction Coupling in Skeletal, Smooth and Cardiac Muscles

18
Q

Calmodulin

A

Locations of each muscle type

19
Q

Myosin light chain kinase

A

Peacemaker potential

20
Q

Function of cardiac muscle

A

Similar to smooth muscle in being involuntary

21
Q

Structure

A

Striated like skeletal muscle

22
Q

Cardiac muscle contraction

A

 Mechanical mechanism similar to that of Skeletal Muscle
◼ Has a “Pacemaker Potential”- Skeletal Muscle does not

23
Q

Ways of activating cardiac muscle

A

-excitatory
-inhibitory
-induced by hormones