Acid Base Reactions Flashcards
Acid base balance
predominantly the result of hydrogen ion concentration ([H+]) and is expressed in manageable quantities as potential hydrogen (pH).
Regulation of acid-base balance resembles that of many other ions in two main ways:
o There must be a balance between intake or production of H+ and net removal from the body.
o The kidneys play a key role in regulating H+ removal from the body, as we saw in our session on ‘Renal Physiology’.
[H+]
Hydrogen ion concentration
What’s plasma and muscle ph
Plasma and muscle pH is maintained between 7.35-7.45 AU
Concentration of h+ comparing to na concentration
Sodium concentration ([Na+]) in extracellular fluid (142 mEq/L) is about 3.5 million times greater than that of H+ (averaging 0.00004 mEq/L).
Weak acid
An acid that demonstrates only a moderate tendency to dissociate.
Conjugate base
What remains after the acid loses its proton (H+).
What’s included in the buffer pair
Weak acid and a conjugate base
Equation between a weak acid and a conjugate base
HA<-→H+ +A-
Association reaction
When [H+] starts to increase, some of the dissolved A- ‘associates’ with free H+ in what is known as the association reaction, expressed as: A- +H+→HA
Dissociation reaction
In the reverse dissociation reaction, dissolved HA ‘dissociates’ in response to declining [H+], releasing H+ as follows:
HA→A- + H+