Heart Cardiac Cycle And ECG Flashcards

1
Q

Function of the heart

A

-Part of the Cardiovascular system
-A physiological pump
• Contributes to overall pressure maintenance (total peripheral resistance, blood flow, heart rate, cardiac output
-Perfusion of orgrans (delivers and removes)

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2
Q

• What is the approximate cardiac output of a healthy 20 year old person?

A

~ 5 - 6 litres/min

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3
Q

Layers

A

Starting from the inside
-endocardium
-myocardium
-visceral layer
-pericardial cavity(space in between) filled with pericardial fluid ,ultra lean plasma which acts as a lubricant
-Parietal layer
Fibrous layer(attached to blood vessels and diaphragm sometimes )

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4
Q

Inside view of the heart

A

4 cardiac chambers
4 valves(made of fibrous tissue)
Tricuspid atrioventricular valve
Mitral atrioventricular valve
Pulmonarv semistinar valve(leads to Pulmonarv artery)
Aortic semi-lunar valve (leads to Aorta)

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5
Q

What does left ventricle generate

A

Highest pressure of all cardiac chambers

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6
Q

Sinoatrial node

A

-Spontaneously depolarising pacemaker
-Located in the Right Atrium at the junction of superior vena-cava)
-Responsible for atrial contraction
-Atrioventricular (AV) node
-In the right posterior portion of inter-atrial septum
-Oversees ventricular contraction

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7
Q

Right coronary artery

A

Supplies blood to
-righy ventricle
-right atrium
-Septum
-sa and av nodes

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8
Q

What does right coronary artery branch to

A

-right posterior descending artery
-marginal artery

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9
Q

Left main coronary

A

Supplies blood to
-left ventricle
-left atrium

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10
Q

What does left main coronary branch into

A

-circumflex artery(encircles the heart muscle,supplies the back and outer side of the heart )
-left anterior descending artery(supplies the front of the left side of the heart)

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11
Q

Myocardial cells

A

-branched
-striated
>lines visible through cells
>indicate the sarcomere edges
-mononucleated
>rich in mitochondria

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12
Q

Myofibril

A

Contains parallel myofilaments

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13
Q

Sarcomere

A

Contractile functional unit
Contains parallel myofilaments

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14
Q

Sarcolemma

A

Muscle cell membrane

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15
Q

Sarcoplasmic reticulum

A

Cells main calcium store

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16
Q

Myocardial filaments

A

-Z disc
Edge of the sarcomere

-M line
Centre of the sarcomere

-1 band
Contains ONLY light myofilaments - Actinband
light
- h zone
-Contains ONLY heavy myofilaments - Myosin

-A band
Contains heavy myofilaments
and overlapping region with actin

17
Q

Myocardial contraction

A

Synchronised contraction of muscle cells
•FIRST in the atria and THEN the ventricles
• Activation of contractile machinery requires calcium
• Calcium cycle used to regulate contraction
Calcium stores:
• Outside the cell - extracellular
• Intracellular calcium store - the (sarco)endoplasmic reticulum

18
Q

Calcium cycle

A

Low calcium in cytoplasm=relaxation
High calcium in cytoplasm=contraction

19
Q

Cardiac circulatory cycle

A

Atrial systole
Early ventricular systole
Ventricular systole
Early ventricular diastole
Ventricular diastole

20
Q

Cardiac output

A

Heart rate x stroke volume

21
Q

Frank starling mechanism

A

-pressure volume loop in the left ventricle during the cardiac cycle
-relationship between blood volume and force required to eject it

22
Q

Positive deflection

A

Current is moving towards electrode

23
Q

Negative deflection

A

Current is moving away from electrode

24
Q

Basic pattern of electrical activity In the heart

A

P wave
Atria depolarisation (Contraction)
QRS interval
Ventricular depolarisation (Contraction)
& Atrial repolarisation (Relaxation)
Q wave - Septal depolarisation
R wave - Depolarisation of the majority of ventricular mass
S wave - Depolarisation of the Purkinje fibres
T wave
Ventricular repolarisation (Relaxation)
U wave
Rare! Late repolarisation
(of Purkinie fibres and some ventricular myocytes)

25
Q

Rate

A

How fast the heart is contracting

26
Q

Rhythm

A

They way it beats