Smoking Cessation Drugs

Question 1

________ a naturally occurring alkaloid, binds stereo-selectively to nicotinic cholinergic receptors at the autonomic ganglia, in the adrenal medulla, at neuromuscular junctions, and in the brain.

Answer 1

Nicotine

Question 2

Treatment to aid smoking cessation for the relief of nicotine withdrawal symptoms (including nicotine craving).

1. Antidepressant
2. Nicotine Replacement therapy (NRT).
3. Partial Nicotine Agonis

Answer 2

Nicotine Replacement therapy (NRT).

Question 3

Is believed to act by enhancing central nervous system noradrenergic and dopaminergic release.

1. Nicotine Replacement therapy (NRT).
2. Antidepressant
3. Partial Nicotine Agonist

Answer 3

Antidepressant

Question 4

What anti depressant is used for smoking cessation?

Answer 4

Bupropion

Question 5

reduces the symptoms of nicotine withdrawal by binding with high affinity and acting as a partial agonist at the alpha -4 beta² nicotinic receptor. It blocks nicotine from binding to the receptor interrupting the reinforcing effects of nicotine that lead to nicotine dependence.

1. Nicotine Replacement therapy (NRT).
2. Antidepressant
3. Partial Nicotine Agonist

Answer 5

Partial Nicotine Agonist

Question 6

Examples of what class?
Varenicline (Chantix)

1. Nicotine Replacement therapy (NRT).
2. Antidepressant
3. Partial Nicotine Agonist

Answer 6

Partial Nicotine Agonist

Question 7

The most common side effects reported of _______ are nausea and disordered sleep, including insomnia and abnormal (vivid, unusual, or strange) dreams.

Answer 7

Varenicline