Psychotherapeutics Flashcards
________ are a class of drugs that cause a dose-dependent depression of the Central Nervous System function, inducing sedation,
sleep, and unconsciousness with increasing dose.
Sedative-hypnotics
_______ depress the sensory cortex, decrease motor activity, alter cerebellar function, and produce drowsiness, sedation, and hypnosis.
Barbiturates
Sedatives and Hypnotics
Using to treat insomnia is NOT recommended for long-term use due to….
risk of dependence
Adverse Effects of what class?
(a) Dependence with long term use
(b) CNS: Somnolence
(c) Respiratory: Hypoventilation
(d) GI: Nausea
(e) CV: Bradycardia
(f) Other: Agitation, confusion, nightmares, lethargy, vomiting, diarrhea, and
hypotension
Sedatives and Hypnotics
What Class are these drugs in?
-barbiturates
-benzodiazepine
-melatonin agonists.
Sedatives and Hypnotics
What would you want to educate your patient about when giving Sedatives and Hypnotics?
Abuse potential
Antianxiety drugs can be subdivided into
_________
_________
Benzodiazepines
Non- Benzodiazepines
Which one is for short term use only?
Benzodiazepines
Non- Benzodiazepines
Benzodiazepines
________ may produce tolerance with long-term use and have potential for psychological or physical dependence. These agents have NO analgesic properties.
- Benzo diazepines
- Non-Benzodiazepines
Benzo diazepines
Benzodiazepines: Bind to specific benzodiazepine receptors in the GABA receptor complex, which enhances ___________
the binding of this inhibitory
neurotransmitter
_____ acts on brain’s dopamine and serotonin receptors
- Benzo
- Non-benzo
Non-Benzo
Long term use of benzodiazepines: Withdrawal syndrome after as little as ______ weeks of therapy. Never discontinue abruptly decrease over _____ weeks
4-6 weeks
Fatigue, metallic taste, HA, numbness in extremities, sweating, and dry mouth are symptoms of withdrawal from _____
- Benzos
- Non- Benzos
- Sedative Hypnotics
Benzos
Contraindication/Warning/Caution for what Drug class?
(a) Should not be used in comatose patients or in those with pre- existing CNS depression. Should not be used in patients with uncontrolled severe pain. Avoid use during pregnancy or lactation.
(b) Acute narrow-angle glaucoma
(c) Pregnancy class: D; Not recommended for use during pregnancy.
(d) Caution with impaired liver or kidney function.
(e) BuSpar and Zolpidem are Pregnancy Class: B
(f) Not to be taken with Alcohol, tricyclic antidepressants, and other antipsychotics.
Antianxiety Drugs
Benzo or Non-Benzo
1) Alprazolam: Xanax
2) Diazepam: Valium
3) Lorazepam: Ativan
Benzodiazepines
Benzo or Non-Benzo
1) Buspirone hydrochloride: Bu Spar
2) Hydroxyzine: Atarax
3) Sertraline (SSRI): May be used long term.
Non-benzos
Patient Management for what class of drug?
(a) Use caution in older patient due to slow excretion.
(b) Benzodiazepines are used primarily in acute situations.
(c) Patient should lie down at least 30 minutes after taking benzodiazepines.
(d) May be taken with or without food or meals.
Antianxiety Drugs
Use of this class of drug
-Sedation
-Seizures: Management of generalized tonic-clonic, status epilepticus and partial
Seizures.
Not recommended to treat insomnia
Sedative and Hypnotics
What Class of drug
Used in the management of various forms of anxiety,
including generalized anxiety disorder.
Antianxiety agents
These fall under what class?
(a) Tricyclic antidepressants (TCAs)
(b) Monoamine Oxidase Inhibitors (MAOI)
(c) Selective Serotonin Reuptake Inhibitors (SSRI)
(d) Serotonin-norepinephrine reuptake inhibitors (SNRIs)
(e) Serotonin Reuptake inhibitor/Antagonist
Antidepressants
______ increase levels of norepinephrine and serotonin by inhibiting their reuptake and blocking the action of acetylcholine.
- SNRI
- SSRI
- MAOI
- TCA
TCA
_____ inhibits the activity of Monoamine oxidase resulting in increased endogenous neuro-hormones.
- SNRI
- SSRI
- MAOI
- TCA
MAOI
_______ increase serotonin by inhibiting neuronal uptake to CNS.
- SNRI
- SSRI
- MAOI
- TCA
SSRI
What Class of drug for these uses?
Depressive symptoms, Anxiety (class dependent), Obsessive Compulsion Disorder, Smoking cessation:
Anti Depressants