Narcotic Analgesics and Antagonist

Question 1

Narcotic analgesics-short term management of _________

Answer 1

moderate to severe pain

Question 2

Action of Narcotic Analgesics
Opioids bind to opiate receptors in the CNS, where they act as agonists of endogenously occurring opioid peptides (endorphins). The result is _____

Answer 2

alteration to the perception of and response to pain.

Question 3

Adverse Effects of Narcotics

Answer 3

(a) Respiratory Depression
(b) Light-headedness
(c) Constipation
(d) Nausea/vomiting

Question 4

Contraindication/Warning/Caution for Narcs

Answer 4

(a) Head injury or increased ICP
(b) Hypoxia
(c) Hepatic impairment
(d) Hypersensitive to opioids or naloxone

Question 5

What do you advise the patient of when giving narcotics?

Answer 5

respiratory risk
risk of constipation

Question 6

Avoid concomitant use of narcotics with what when possible?

Answer 6

benzodiazepines or other CNS depressants

Question 7

Opioid agonist or Antagonist?
(a) Partial Agonist: Buprenorphine
(b) Codeine: Codeine
(c) Fentanyl: Sublimaze
(d) Hydromorphone: Dilaudid
(e) Methadone: Dolophine
(f) Morphine sulfate: MS Contin
(g) Oxycodone: OxyContin
(h) Hydrocodone: Norco, Lortab, and Vicodin

Answer 7

agonist

Question 8

___________ is a commonly used opioid antagonist drug which is competitive antagonists that bind to the opioid receptors with higher affinity than agonists
but do not activate the receptors. This effectively blocks the receptor, preventing the body from responding to opiates and endorphins.

Answer 8

Naloxone

Question 9

What is a Narcotic Antagonist used for?

Answer 9

Overdose of a Narcotic

Question 10

What is an adverse effect to Narcotic Antagonist

Answer 10

Acute opioid withdrawal

Question 11

Contraindication for Narcotic Antagonist

Answer 11

Hypersensitivity to naloxone or any component of the formulation

Question 12

Use naloxone with caution in patients with _______,
______ women, and opioid dependent patients.

Answer 12

CAD
Pregnant Women