small RNAs Flashcards

1
Q

central

A

dogma

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2
Q

siRNA polymerase

A

RDRP2

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3
Q

de novo dna methylation

A

MET1: CGs
DRM2: non-CGs

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4
Q

DNA methylation maintenance

A

MET1
CRM2

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5
Q

DNA Methylation reactivation

A

ROS1/DME from DNA glycosylase

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6
Q

Example of RNAi-mediated DNA methylation

A
  • ONSEN TF is unregulated under heat stress
  • controlled by RDDM
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7
Q

uses of small RNAs

A
  • gene silencing sprays for pest/pathogen resistance
  • pesticides for Varroa mite and Colorado potato beetle
  • superior to GM because of lack of legislative concerns, biodegradable and met bioavailable to plants
  • anti-miRNAs in cancer therapeutics
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