small RNAs Flashcards
1
Q
central
A
dogma
2
Q
siRNA polymerase
A
RDRP2
3
Q
de novo dna methylation
A
MET1: CGs
DRM2: non-CGs
4
Q
DNA methylation maintenance
A
MET1
CRM2
5
Q
DNA Methylation reactivation
A
ROS1/DME from DNA glycosylase
6
Q
Example of RNAi-mediated DNA methylation
A
- ONSEN TF is unregulated under heat stress
- controlled by RDDM
7
Q
uses of small RNAs
A
- gene silencing sprays for pest/pathogen resistance
- pesticides for Varroa mite and Colorado potato beetle
- superior to GM because of lack of legislative concerns, biodegradable and met bioavailable to plants
- anti-miRNAs in cancer therapeutics