SM_157b: Liver Tumors

Question 1

Primary cancer of hepatocytes is ____ or ____

Answer 1

Primary cancer of hepatocytes is adenoma or hepatocellular carcinoma

Question 2

Primary cancer of bile ducts is ____ or ____

Answer 2

Primary cancer of bile ducts is adenoma or cholangiocarcinoma

Question 3

Primary cancer of blood vessels in liver is ____ or ____

Answer 3

Primary cancer of blood vessels in liver is hemangioma or angiosarcoma

Question 4

This neoplasm is ____

Answer 4

This neoplasm is hepatocellular carcinoma

Question 5

This neoplasm is ____

Answer 5

This neoplasm is hepatocellular carcinoma

Question 6

This neoplasm is ____

Answer 6

This neoplasm is hepatocellular carcinoma

Question 7

This neoplasm is ____

Answer 7

This neoplasm is hepatocellular carcinoma

Question 8

Hepatocellular carcinoma pathology involves ____, ____, ____, and ____

Answer 8

Hepatocellular carcinoma pathology involves

• No normal portal tract
• Hepatocytes growing in haphazard pattern
• Hepatic plate expansion
• Has potential to metastasize

Question 9

____ is the most common primary hepatic malignancy of adults

Answer 9

Hepatocellular carcinoma is the most common primary hepatic malignancy of adults

• Risk factors: male, Hepatitis B, Hepatitis C, aflatoxin, cirrhosis

Question 10

____ often presents as a solitary mass in a background of cirrhosis

Answer 10

Hepatocellular carcinoma often presents as a solitary mass in a background of cirrhosis

Question 11

____ is elevated in hepatocellular carcinoma and germ cell neoplasms

Answer 11

Alpha-fetoproteins is elevated in hepatocellular carcinoma and germ cell neoplasms

Question 12

This neoplasm is ___

Answer 12

This neoplasm is hepatocellular adenoma

Question 13

This neoplasm is ___

Answer 13

This neoplasm is hepatocellular adenoma

Question 14

Hepatocellular adenoma involves ____ portal tract, hepatocytes growing in ____, and ____ metastasize

Answer 14

Hepatocellular adenoma involves NO normal portal tract, hepatocytes growing in relatively normal pattern, and NO potential to metastasize

• Risk factor: elevated levels of hormones (OCPs, steroids)

Question 15

This neoplasm is ____

Answer 15

This neoplasm is cholangiocarcinoma

Question 16

Chalgiocarcinoma arises from ____

Answer 16

Chalgiocarcinoma arises from bile ducts anywhere within the biliary tree

• Risk factors: diseases that cause chronic inflammation of the biliary tree

Question 17

Cholangiocarcinoma pathology involves ____ and ____

Answer 17

Cholangiocarcinoma pathology involves loss of normal hepatocytes and bile ducts and fibrous stroma with malignant appearing ducts

Question 18

____ is the most common benign neoplasm of the liver and involves proliferation of vascular spaces

Answer 18

Hemangioma is the most common benign neoplasm of the liver and involves proliferation of vascular spaces

Question 19

Portal venous phase demonstrating gradual centripetal contrast enhancement on CT is ____

Answer 19

Portal venous phase demonstrating gradual centripetal contrast enhancement on CT is hemangioma

Question 20

This liver neoplasm is ____

Answer 20

This liver neoplasm is hemangioma

Question 21

This neoplasm is ____

Answer 21

This neoplasm is hepatoblastoma

Question 22

____ is the most common liver tumor of early childhood

Answer 22

Hepatoblastoma is the most common liver tumor of early childhood

• Single liver mass
• Rarely occurs after age 3
• fzrequent activation of WNT signaling pathway: mutation in downstream of WNT signaling (APC gene)
• Patients with FAP frequently develop hepatoblastoma

Question 23

This neoplasm is ____

Answer 23

This neoplasm is metastatic colon cancer

Question 24

Metastatic colon cancer is often ____ and often forms ____

Answer 24

Metastatic colon cancer is often multiple and often forms glands with dirty necrosis in the glandular spaces

• Common tumors that metastasize to liver: colon, lung, breast
• Spread occurs through blood vessels