Sleep Flashcards

1
Q

What are the stages of the sleep cycle?

A
  • Stages 1-4 of the NREM sleep

- REM sleep

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2
Q

What occurs in NREM sleep?

A
  • it is said to be DEEP sleep
  • period of REDUCED HR, cerebral BLOOD FLOW, BP, tidal volumes
  • Partial muscle relaxation
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3
Q

How is the EEG pattern for NREM sleep?

A
  • synchronised, RHYTHMIC EEG activity
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4
Q

What occurs in REM sleep?

A
  • increased BRAIN activity (similar to when ONE’s AWAKE)
  • increased CEREBRAL blood flow
    -impaired THERMAL regulation
    -atonic muscles
    (except diaphragm and extraocular m)
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5
Q

At what stage does Narrative dreaming occur and why is that convenient?

A
  • during REM
  • because its the stage at which MUSCLES in the body are ATONIC; therefore one wouldn’t be able to ACT out in their sleep
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6
Q

Which stage is important?

A

The 4 NREM stages

  • time of deep sleep
  • only time where lost sleep is REGAINED
  • allows RECOVERY of cortex after a LONG day
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7
Q

When is REM sleep important?

A

it is important for early brain development- not needed for HIGHLY functioning brain

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8
Q

What changes occur throughout to one’s sleep cycle as you grow older?

A
  • neonates: 50% REM sleep (shorter cycles)

- elderly: REDUCED REM latency (INCREASED awakenings)

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9
Q

What is the role of REM with memory storage?

A
  • REM sleep CONSOLIDATES memory and “deletes” unnecessary memory
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10
Q

What other physiological role does REM sleep hold true, esp. with Elderly people?

A
  • maintains IMMUNOCOMPETENCE (why older people become more become more frail)
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11
Q

What physiological process is NREM involved in?

A
  • PROTEIN synthesis

- cell division and growth

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12
Q

What controls the circadian rhythm?

A
  • appetite, body T*, hormone secretions

- LIGHT entrains the body clock(by using the retinal GANGLION cells)

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13
Q

Does sleep have any physiological role in muscle processing?`

A
  • sleep helps with TISSUE repair; cell division peaks during sleep
  • GH increases during NREM sleep
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14
Q

What occurs with lack of sleep?

A
  • PREFRONTAL effects such as one gets IRRITABLE
  • have VISUAL ILLUSIONS
  • microsleeps and LOSS of concentration
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15
Q

What exact function is impaired in the Prefrontal cortex?

A
  • routine and logical tasks are not affected!

- ALERTNESS is affected

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16
Q

What occurs with sleep deprivation?

A
  • more LETHARGIC
  • wgt loss (despite eating more)
  • skin ulceration and injury
  • ?hypothermia/reduced immunity
17
Q

Sleep is a deadly killer in ______

A

RTAs

18
Q

Most suitable hours of sleep?

A

7-7.5 hrs

19
Q

How much is a mid-afternoon nap of 15mins worth?

A

90mins overnig[ht sleep

20
Q

What are the 2 types of Parasomnias?

A

NREM and REM

21
Q

What are the signs and symptoms of NREM parasomnias?

A
  • non-dreamin
  • confusional arousals
  • sleep walking, TERRORS
  • BRUXISM—grind teeth
  • RESTLESS LEGS
22
Q

What is seen in REM parasomnia? And in whom?

A
  • in latter 1/3 of night
  • Nightmares
  • sleep paralysis
  • at any age; in children with PTSD or ANXIETY disorder.
23
Q

Which parasomnia precedes Parkinson’s Disease?

A

REM parasomnias

24
Q

What occurs in Narcolepsy?

A
  • involuntary solmonence when EATING/TALKING
  • HARD TO RESIST
  • CATAPLEXY (70% of pts)
  • hypnagogic halluncinations
  • sleep paralysis
  • RBD
25
Q

When is the age of ONSET for narcolepsy ?

A

50% of adults have symptoms teenager

26
Q

What is Narcolepsy a/w?

A
  • REM sleep Behaviour d/o (RBD)
27
Q

What IVX are done for Narcolepsy?

A
  • sleep test (Overnight Polysomnography)
  • Multiple sleep Latency test (4 twenty-five min NAPS schedules 2 hrs apart )——-record EEG, muscle activity and eye movement recorded
28
Q

How may a LP indicate nARCOLEPSY ?

A

LOW CSF hypocretin levels (<110pg/ml)

29
Q

Name examples of REM sleep behaviour d.o.

A

D.t to LOSS of muscle paralysis during REM sleep (seen usually); person will start to act out!

  • kick/ punch/slap in bed whilst still asleep
  • shout/ leap out
  • act out actions of dreams they clearly RECALL
30
Q

RBD is often seen in what demographic.

Which 2 conditions often present with RBD?

A
  • in men (<50 y.o)

- PARKINSON’s and MULTIPLE SYSTEM ATROPHY

31
Q

How to differentiate epilepsy from NREM/ REM sleep behavioural disorder?

A
  • conducting a Polysomnography and EEG montage

- eyes are OPEN during an epileptic seizure accompanied by a post-ictal state of confusion

32
Q

Name the 3 types of dissociative disorders.

A
  1. Dissociative d.o of MOvement
  2. Dissociative AMNESIA
  3. Dissociative IDENTITY disorder
33
Q

What are some symptoms of dissociation?

A
  • amnesia
  • depersonalisation
  • derealisation
  • identity Confusion
  • indentity alteration
  • loss of FEELINGS
  • losing control of BODY movements
34
Q

What occurs with dissociative amnesia?

A
  • pt does NOT remember things that have happened to them (memory LAPSE)
  • related to a traumatic event
35
Q

How is dissociative disorder different from a psychotic patient?

A
  • Dissociative patients are AWARE
36
Q

What is obstructive sleep apnea?

A
  • sleep d.o that causes you to stop breathing during sleep

- –random closure of airway > SNORING or CHOKING noises

37
Q

What may contrubute to obstructive sleep apnea?

A
  • sleeping on your back

- tongue falls back, narrowing the airway