Sleep Flashcards

1
Q

What are the two types of sleep?

A

REM and nonREM

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2
Q

What sleep is the most important type of sleep?

A

nonREM - allows brain recovery

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3
Q

What sleep happens at the start of the night?

A

non REM

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4
Q

What sleep happens at the end of the night?

A

REM

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5
Q

What happens during non REM sleep?

A

synchronised, rhythmic EEG activity
partial muscle relaxation
reduced cerebral blood flow
non narritive dreaming

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6
Q

What happens during REM sleep?

A

EEG shows fast activity
MRI shows increased brain activity
loss of muscle tone - except diaphragm and extraocular muscles
narritive dreaming - you’re part of the story
increased cerebral blood flow
impaired thermal regulation

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7
Q

What type of sleep do tricyclic drugs surpress?

A

REM sleep

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8
Q

What are the 3 things that trigger sleep onset?

A

homeostatic response - body is tired
circadian rhythm - body clock
emotional response - brain needs to swich off fully for deep sleep

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9
Q

What happens to elderly peoples sleep pattern?

A

reduced REM latency
reduced total sleep time
increased daytime sleepiness - napping
advanced sleep pattern

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10
Q

What percentage of REM sleeps do neonates and adolesents have?

A

neonates - 50%

adolescents - 25%

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11
Q

What dictates the circandian rhythm?

A

in the eyes there is a cell - not a cone or a rod cell - that is very sensitive to a particular frequency of low level light - this resets the body clock

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12
Q

What is the role of nonREM sleep?

A

protein synthesis
cell division
growth

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13
Q

What is the role of REM sleep?

A

consolidate memory
maintain immunocompetence
possibly deletes unecessary memory files

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14
Q

What area of the brain does sleep deprivation affect the most?

A

pre frontal area

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15
Q

How does sleep deprivation present?

A
visual illusions
irritability
suspiciousness
micro sleeps
concentration lapses
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16
Q

How do nonREM parasomnia present?

A
non dreaming
confusional arousal
sleep walking
sleep paralysis
Bruxism
restless legs
PLMS
17
Q

How do REM parasomnia present?

A

proceeds Parkinson’s
acting out dreams
usually latter 1/3rd of the night
body isnt fully relaxed

18
Q

What type of parasomnia will every Parkinson patient have?

A

REM parasomnia

19
Q

What are the two peak age of onsets for Narcolepsy?

A

15 and 36

20
Q

How does Narcolepsy present?

A

involuntary daytime sleepiness
cataplexy - collapse with any sense of emotion
hypnagogic hallucinations occur at sleep onset
sleep paralysis - retain conciousness but cannot move
REM behaviour disorder

21
Q

How is Narcolepsy mainly investigated?

A

multiple sleep latency test - 4 x 25 min naps about 2 hours apart
EEG, muscle activity and eye movement recorded
measures start time of the nap to the first signs of sleep

22
Q

What else can you do to investigate narcolepsy?

A

overnight polysonography

lumbar puncture - low CSF hypocretin levels