Peripheral Neuropathy Flashcards

1
Q

What is a radiculopathy?

A

nerve root damage

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2
Q

What is a plexopathy?

A

plexus damage

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3
Q

What are the 3 types of peripheral neuropathy?

A

mononeuropathy
mononeuritis multiplex
length dependant peripheral neuropathy

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4
Q

Describe the pattern seen in length dependant peripheral neuropathy?

A

glove and stocking distribution

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5
Q

Are large motor and sensory fibres myelinated or unmyelinated?

A

myelinated

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6
Q

What is the presentation of a large motor fibre lesion?

A
weakness
unsteadiness
wasting
reduced power
absent reflexes
normal sensation
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7
Q

What is the presentation of a large sensory fibre lesion?

A
numbness
parasthesia
unsteadiness
normal power
vibration and JPS sensation reduced
reflexes absent
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8
Q

Are small fibres myelinated or unmyelinated?

A

thinly myelinated - cold perception and pain

unmyelinated - warm perception and pain

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9
Q

What is the presentation of a small fibre lesion?

A

pain
dyesthesia - abnormal sensation when being touched
normal power
pin prick and temperature sensation reduced
reflexes present

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10
Q

Are autonomic fibres myelinated or unmyelinated?

A

either thinly myelinated or unmyelinated

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11
Q

What is the presentation of an autonomic fibre lesion?

A
dizziness
impotence
nausea
vomiting
normal power, sensation and reflexes
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12
Q

How are nerve problems tested?

A

nerve conduction studies

electromyography

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13
Q

How are nerves damaged (e.g. the lesions)?

A

axonal loss

demyelination

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14
Q

What is an acute form of demyelinating neuropathy?

A

Guillian Barre Syndrome

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15
Q

What is a chronic form of chronic demyelinating neuropathy?

A

Chronic inflammatory demyelinating polyrediculopathy

hereditory sensory motor neuropathy

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16
Q

What is the presentation of GBS?

A

progressive paraplegia (days-4weeks) - peak of symptoms are 4 weeks in
sensory symptoms proceed weakness and pain is common
TOTALLY REVERSIBLE

17
Q

What causes GBS?

A

may be post infectious - cambylobacter

strips the autonomic system of its function so may develop arrythmias and die

18
Q

What is the treatment of GBS?

A

immunoglobulin infusion

plasma exchange

19
Q

What causes hereditory sensory motor neuropathy?

A

autosomal dominant or autosomal recessive or X linkes

common mutations CMT1a

20
Q

How does hereditory sensory motor neuropathy present?

A

muscle atrophy around peripheral limbs - champagne bottle appearance
sensory loss and progressive distal weakness