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PYT-Derma > Skin-anatomy > Flashcards

Skin-anatomy Flashcards

1
Q

Epidermis & dermis are derived from?

A

Epidermis → ectoderm
Dermis → mesoderm

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2
Q

Principle cells of epidermis?

A

Keratinocytes - 90% of epidermal cells

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3
Q

Dermis contains which collagen?

A

Type 1 → 80%
& 3 → 10 -20%
Ratio of → 4:1

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4
Q

Skin weight?

A

12 - 16% of total body weight

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5
Q

Naive the layers of epidermis?

A

Corneum
Lucidum
Granulosum
Spinosum
Basale

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6
Q

Stratum Malpighi?

A

Stratum battle & stratum spinosum

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7
Q

Intracellular edema of keratinocytes in ?
Stratum basale?
Stratum spinosum?

A

St. Basale → ballooning
St. Spinosum → spongiosis → ch. Of eczema

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8
Q

Layer absent in premature neonate?

A

St. Corneum

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9
Q

Layer with highest concentration of free amino acids ?

A

Stratum corneum

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10
Q

What is parakeratosis??

A

Retention of nuclei in stratum corneum

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11
Q

Define hyper keratosis?

A

Thickening of stratum corneum

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12
Q

Keratin is mostly synthesized in ?

A

Stratum spinosum

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13
Q

Layer containing refractive droplets of eleidin?

A

Stratum lucidum

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14
Q

What are rete ridges?

A

Downgrowths of epidermis folds into dermis

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15
Q

Layers of dermis?

A

Papillary & reticular

Papillary → superficial layer → contains loose areolar tissue , superficial capillaries & nerve endings

Reticular → deep layer → contains collagen, elastic fibres, appendages, arterioles & venules

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16
Q

Subcutaneous tissue?

A

Consists of fat
Attached to deep fascia
Thickest → in palms & soles
Thinnest → in eyelids

17
Q

Describe cells in epidermis?
Where are they derived from?

A

Local cells → keratinocytes → develop from ectoderm
Immigrant cells → melanocytes→ neural crest cells →→→ develop elsewhere & migrate to epidermis
→ Merkle calls → neural crest cells
→ langerhan cells → derived from mesenchyme

18
Q

Keratinocytes?

A

Proliferate (divide) → in basal layer
Differentiate in → stratum spinosum & stratum granulosum
Completely mature & die in → stratum corneum

19
Q

Melanocytes

A

Max number is in → skin of genitalia

20
Q

Langerhan cells

A

These are APC → in stratum spinosum
Reduced in » aging, bcc, SCC, sarcoidosis & aids
Increased in → oral lichen planus, langerhau cell histiocytosis, contact hypersensitivity

21
Q

Merkle cells

A

Slow adapting touch receptors
Present in basal layer

PYT-Derma (35 decks)

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