Acanthosis Nigricans

Question 1

Its a cutaneous marker of?

Answer 1

Insulin resistance & obesity
Genetic disorder & malignancy less frequently

Question 2

Describe lesion

Answer 2

Symmetrical grey-brown velvety plaques
With feathered margins
Looks like dirty appearing hyperpigmentation

Question 3

Hereditary an

Answer 3

AD inheritance

Question 4

Hair - AN syndrome

Answer 4

Hyper androgenism
Insulin resistance
Acanthosis Nigricans

Question 5

M/C/C

Answer 5

Obesity - benign acquired an

Question 6

Drug induced AN

Answer 6

Corticosteroids
OCPs
Nicotinic acid
Stilbesterol

Question 7

Malignant AN

Answer 7

Adenocarcinoma stomach → mc malignancy

Question 8

Sites of predilection?

Answer 8

Back of neck is → m. Consistently & severely affected area
Neck, axilla, groin, antecubital & popliteal fossa, face, submammary folds , wrist

Question 9

What are tripe palms?
Indicate?

Answer 9

If involve knuckles & palms → rugated app → c/a tripe palms → indicative of malignancy

Question 10

Involves vulva in?

Answer 10

Obese, hirsute, hyperandrogenic & insulin resistant woman