DLE

Question 1

What is DLE?

Answer 1

Dis. in which skin manifestation → may mimic SLE but systemic manifestations are rare

Question 2

Skin lesions seen at?

Answer 2

Face, scalp & external ears

Question 3

Describe the lesion?

Answer 3

Well demarcated
Discoid/ annular
Erythematous plaque
With adherent scales
Centre of lesion - atrophic ,scarred & depigmented with telangiectasia
Active border - is elevated, shows lilac erythema & hyperpigmentation
Persist for years & tend to expand slowly

Question 4

Etiology?
Aggravating factor?

Answer 4

Etio → unknown
Aggravates on → UV exposure →.: photo protection is imp.

Question 5

Explain carpet tack sign?

Answer 5

When scale is removed → its undersurface shows keratotic spikes → that have occupied dilated pilosebaceous canals

Question 6

Dx?
Direct immunofluorescene?

Answer 6

Biopsy
Linear deposits of ig G,M,A & C3 at dermoepidermal junction

Question 7

Histopath?

Answer 7

Hyper keratosis
Epidermal atrophy with follicular plugs
Basal cell degeneration
Perivascular & periappendageal lymphocytic infiltrate

Question 8

Treatment?

Answer 8

Local lesion → topical or intralesional steroids
Resistant or disseminated lesion → hydroxychloroquine