Skeletal Muscle Relaxants Flashcards
Nondepolarizing NM blockers
Tubocararine, mivacurium, atracurium, vecuronium, rocuronium, pancuronium
Only depolarizing muscle relaxant
Succinylcholine
MOA of Nondepolarizing blocksfs
Competitive antagonists at skeletal muscle nicotinic Ach receptors
Use of NM blockers
Relaxation for anesthesia and general anesthesia
Nondepolarizing NM blocker’s effects are reversed by
Neostigmine
Undergoes hoffman elimination
Atracurium
Elimination in bile
Vecuronium
Novel reversal agent for rocuronium
Sugammadex
Moderate block on cardiac muscarinic receptors
Pancuronium
Used in euthanasia, legal injection, strychine poisoning
Pancuronium
MOA of depolarizing NM blockers
Agonist at ACH- N receptors causing initial twitch then persistent depolarizatiob