Antibitoics Flashcards
May cause red man syndrome
Vancomycin
Inhibits bacterial cell wall synthesis by binding to D Ala D ala terminus of nascent peptidoglycan
Vancomycin
Peptide antibiotic that interferes with a late stage in cell wall synthesis in gram positive organism
Bacitracin
Antimetabolite, blocks incorporation of D ala into pentapeptise side chain of peptidoglycan
Cycloserine
May cause aplastic anemia and gray baby syndrome
Chloramphenicol
DOC for rickettsiae
Tetracycline
May cause tooth enamel dysplasia/discoloration
Tetracycline
Tetracycline should not be taken with
Milk
Only macrolide that does not inhibit CYP450
Azithromycin
Cross resistance b/n clindamycin and wc drug is commkn
Macrolide
Binds to 50s subunit. BACTERICIDAL
Quinupristin- dalfopristin
Basis for once daily aminoglycoside dosing
Post antibiotic effect
Has narrowest therapeutic window among aminoglycosides
Amikacin
Aminoglycoside used for endocarditis
Gentamicin
Aminoglycoside used for multi drug resistant TB
Amikacin