Antihypertensive

Question 1

inhibit na/cl transporter in distal convoluted tubules. reduce excretion of calcium. for hypertension ( first line).

Answer 1

hydrochlorothiazide

Question 2

loop diuretic. inhibit na/k/2cl in thick ascending loop of henle. powerful diuresis and increase ca excretion. for heart failure, PULMONARY EDEMA.

Answer 2

furosemide

Question 3

activates a2 which decreases central symphatetic outflow. for hypertension. side effect: Rebound hypertension,

Answer 3

clonidine

Question 4

activates a2 adrenergic receptor. for Pre Eclampsia. Se: sedation, Hemolytic Anemia

Answer 4

methyldopa

Question 5

ganglion blocker, competitively blocks nicotinic ach receptors. for Hypertension (obsolete). SE: Postural Hypertension, dry mouth.

Answer 5

hexamethonium

Question 6

nerve terminal blocker, irreversibly blocks the vesicular monoamine transporter(vmat) for Hypertension. (obsolete) SE: sedation, Suicidal Ideation.

Answer 6

reserpine

Question 7

adrenergic antagonist A1 selective. for BPH, hp. SE: first dose orthostatic hypotension.

Answer 7

prazosin

Question 8

blocks b1 and b2 receptors. for angina prophylaxis, Hypertension, arrhytmias, migraine. may mask hypoglycemia in diabetics.

Answer 8

propranolol

Question 9

vasodilator, relaxes arteriolar smooth muscle, causing vasodilation, for hypertension, heart failure. SE: edema, reflex tachycardia, MI, Drug Inducrd Lupus

Answer 9

hydralazine

Question 10

vasodilator, open k+ in vascular smooth muscle causing relaxation and vasodilation. for hypertension, Alopecia. SE: Hypertrichosis, pulmonary hpn, pericarditis.

Answer 10

minoxidil

Question 11

block voltage gated L type calcium channel. for Supraventricular Tachycardia, migraine. SE: Gingival Hyperplasia, pretibial edema, av block

Answer 11

verapamil

Question 12

block L type calcium channels. for Angina, Hypertension. SE: Pretibial edema, nausea, flushing, dizziness

Answer 12

nifedipine

Question 13

vasodilator. for Hypertensive Emergency, acute heart failure, cardiogenic shock. SE: Cyanide toxicity

Answer 13

nitroprusside

Question 14

dopamine agonist, causes vasodilation of afferent and efferent arterioles, for Hypertensive emergency. SE: hypotension, hypokalemia

Answer 14

fenoldam

Question 15

ace inhibitor, for Hypertension, heart failure, post MI, diabetic nephropathy. * delays progression of DM nephropathy.

Answer 15

captopril

Question 16

angiotensin receptor blocker, for hypertension, heart failure, diabetic nephropathy SE: hypotension, teratogen, hyperkalemia

Answer 16

losartan

Question 17

renin antagonist. for hypertension, SE: headache, diarrhea,Angioedema, renal impairment.

Answer 17

aliskiren