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Skin & MSK > Skeletal Disorders > Flashcards

Skeletal Disorders Flashcards

1
Q

Bone matrix is osteoid made of this

A

Type I collagen

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2
Q

These cells form new bone on surface of osteoid

A

Osteoblasts

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3
Q

These cells become osteocytes when senescent

A

Osteoblasts

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4
Q

These cells secrete acids into resorption pit to absorb bone and release calcium

A

Osteoclasts

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5
Q

Osteoclasts are derived from this

A

Hematopoietic cells, monocyte/macrophage

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6
Q

Type of bone formation that occurs in long bones

A

Endochondral

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7
Q

Fibroblast growth factor 3 promotes differentiation of these

A

Chondrocytes

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8
Q

Type of bone formation where growing cartilage at epiphyseal plates have provisional mineralization
Apoptotic chondrocytes are replaced by ingrowth of osteoblasts

A

Endochondral

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9
Q

Fibroblast growth factor 3 promotes this type of bone formation

A

Endochondral

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10
Q

Type of bone formation that occurs in flat bones

A

Intramembranous

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11
Q

Type of bone formation where mesenchymal cells differentiate into osteoblasts and pre-existing matrix undergoes mineralization

A

Intramembranous

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12
Q

Before remodeling, initial bone is of this type

A

Woven

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13
Q

These cells are activated by WNT/Beta-catenin signaling

A

Osteoblasts

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14
Q

Calcium deposition is mediated by this

A

Alkaline phosphatase

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15
Q

Alkaline phosphatase mediates the deposition of this

A

Calcium

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16
Q

Osteoblasts are activated by signaling of this

A

WNT/Beta-catenin

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17
Q

Parathyroid hormone stimulates these cells

A

Osteoclasts

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18
Q

Stimulation of RANK receptor activates these cells

A

Osteoclasts

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19
Q

Osteoclasts are activated by stimulation of this receptor

A

RANK

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20
Q

These cells are activated by M-CSF

A

Osteoclasts

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21
Q

What effect does estrogen have on bone mass?

A

Is protective

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22
Q

What effects does Vitamin D have on Calcium?

A

Increases renal Ca reabsorption
Increases bone deposition of Ca

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23
Q

Vitamin D increases bone deposition of Ca via osteoblast production of this calcium binding protein

A

Osteocalcin

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24
Q

This increases bone deposition of Ca via osteoblast production of the Ca binding protein osteocalcin

A

Vitamin D

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25
Q

Vitamin D increases bone deposition of Ca via these cells producing osteocalcin (Ca binding protein)

A

Osteoblast

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26
Q

Alkaline phosphatase is increased when this is occuring

A

Increased in bone deposition/turnover
E.g. tumor

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27
Q

What effect does Parathyroid Hormone have on bone resorption?

A

Causes bone resorption

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28
Q

These are precursors to osteoblasts

A

Mesenchymal cells

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29
Q

Osteoblasts or Osteoclasts?:
Eccentric nuclei

A

Osteoblasts

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30
Q

Osteoblasts or Osteoclasts?:
On osteoid surface

A

Osteoblasts

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31
Q

Osteoblasts or Osteoclasts?:
Mineralize bone with alkaline phosphatase

A

Osteoblasts

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32
Q

Osteoblasts or Osteoclasts?:
Osteocyte is senescent form

A

Osteoblasts

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33
Q

Osteoblasts or Osteoclasts?:
Monocytes are precursors

A

Osteoclasts

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34
Q

These are precursors to Osteoclasts

A

Monocytes

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35
Q

Osteoblasts or Osteoclasts?:
Multinucleated

A

Osteoclasts

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36
Q

Osteoblasts or Osteoclasts?:
Form resorption pits

A

Osteoclasts

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37
Q

Osteoblasts or Osteoclasts?:
Release Ca and P into serum

A

Osteoclasts

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38
Q

Type of bone:
Newly formed bone, disorganized, not as strong

A

woven bone

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39
Q

Type of bone:
Mature bone after remodeling, increased strength, compact bone cortex, cancellous in medullary cavity

A

Lamellar bone

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40
Q

Bone marrow fills this part of bone

A

Medullary cavity

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41
Q

What effect does RANK/RANK-L have on bone?

A

Stimulates bone resorption by osteoclasts

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42
Q

RANK/RANK-L stimulates bone resorption by these

A

Osteoclasts

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43
Q

Decoy molecule that inhibits bone resorption
Protects bone

A

Osteoprotegerin

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44
Q

This promotes osteoclast mediated bone resorption via increased RANK/RANK-L

A

PTH

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45
Q

This decreases RANK/RANK-L, increases osteoprotegerin

A

Estrogen

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46
Q

Most common form of dwarfism

A

Achondroplasia

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47
Q

Inheritance pattern of Achondroplasia

A

Autosomal dominant

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48
Q

Condition caused by a gain of function in FGF3 receptor
Most are new sporadic paternal mutations (advanced paternal age)

A

Achondroplasia

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49
Q

Gain of function in this can cause Achondroplasia

A

FGF3

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50
Q

What effect does Achondroplasia have on long bones?

A

Promotes endochondral ossification, so there is presence of shortened long bones - short extremities
Normal flat bones

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51
Q

More severe, lethal form of dwarfism

A

Thanatophoric dysplasia

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52
Q

What causes Achondroplasia?

A

Gain of function in FGF3 receptor

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53
Q

What causes Thanatophoric dysplasia?

A

Gain of function FGF3 mutation with greater effect

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54
Q

This condition has similar features as Achondroplasia, but death occurs in neonatal period due to respiratory insufficiency

A

Thanatophoric dysplasia

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55
Q

What causes Osteogenesis Imperfecta?

A

Switch of glycine with non-gly amino acid in type I collagen
Impairs formation of triple helix

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56
Q

Condition caused by a switch of glycine with a non-gly amino acid in collagen, impairing the formation of the triple helix

A

Osteogenesis Imperfecta

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57
Q

What type of collagen is affected in Osteogenesis Imperfecta?

A

Type I

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58
Q

What is the inheritance pattern of Osteogenesis Imperfecta?

A

Dominant negative

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59
Q

Condition that is also called Brittle bone disease

A

Osteogenesis Imperfecta

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60
Q

Condition where fusion of conductive ossicles may occur, leading to conductive hearing loss

A

Osteogenesis Imperfecta

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61
Q

Condition that can have thin, transparent sclera with visualization of underlying choroid vasculature = blue sclera

A

Osteogenesis Imperfecta

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62
Q

Blue sclera is seen in this condition

A

Osteogenesis Imperfecta

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63
Q

Diffuse skeletal sclerosis due to defective osteoclast absorption

A

Osteopetrosis

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64
Q

Osteopetrosis is diffuse skeletal sclerosis due to a defect in this

A

Osteoclast absorption

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65
Q

Condition where defective osteoclast absorption results in no bony remodeling

A

Osteopetrosis

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66
Q

Carbonic Anhydrase deficiency may cause this skeletal condition

A

Osteopetrosis

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67
Q

Why can Carbonic Anhydrase deficiency cause Osteopetrosis?

A

Deficiency results in lack of acidic environment in resorption pit
(also results in renal tubular acidosis)

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68
Q

Condition were there is a lack of bone resorption, so bone is DENSE

A

Osteopetrosis

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69
Q

Condition where neural foramen may be occluded, causing cranial nerve defects

A

Osteopetrosis

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70
Q

Condition where there is extremely sclerotic bone with no medullary cavity for hematopoiesis, leading to low platelet, WBC, etc. counts

A

Osteopetrosis

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71
Q

What is the treatment for Osteopetrosis?

A

Bone marrow transplant

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72
Q

What are the levels of platelets and WBCs in Osteopetrosis?

A

Low
Extremely sclerotic bone has no medullary cavity for hematopoiesis
Extramedullary hematopoiesis may occur

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73
Q

Condition described by a bone density less than 2.5 std below mean peak bone density of young adults

A

Osteoporosis

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74
Q

What race is most affected by Osteoporosis?

A

Caucasians
Much less common in African races

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75
Q

Risk of Osteoporosis is determined by these two factors

A

Peak bone mass at early adulthood
Rate of age-related bone loss

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76
Q

Primary or secondary Osteoporosis?:
Senile - males especially
Post-menopausal (estrogen deficiency)

A

Primary

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77
Q

Primary or secondary osteoporosis:
Can be caused by hyperparathyroidism, neoplasm, intestinal disorders with malabsorption, chronic steroid use, hypogonadism

A

Secondary Osteoporosis

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78
Q

Chronic steroid use increases risk of this condition

A

Secondary Osteoporosis

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79
Q

Condition where there is normal bone but less of it
Most significant change at lumbar/thoracic vertebral bodies

A

Osteoporosis

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80
Q

What are the levels of Ca, PTH, and Alkaline phosphatase in Osteoporosis?

A

All normal

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81
Q

Biphosphonates inhibit these and can be used as treatment for Osteoporosis

A

Osteoclasts

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82
Q

Biphosphonates inhibit osteoclasts and can be used as treatment for this condition

A

Osteoporosis

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83
Q

Condition characterized by normal amount of bone matrix but inadequate mineralization

A

Rickets/Osteomalacia
Usually caused by Vitamin D deficiency

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84
Q

In children, does Rickets affect endochondral or membranous bone?

A

Both

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85
Q

What are the levels of Ca, Phosphate, Alk phos, and PTH in Rickets/Osteomalacia?

A

Low/normal Ca
Low phosphate
High alk phos
High PTH

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86
Q

Normal levels of Ca, PTH, and alk phos but with low bone density indicate this condition

A

Osteoporosis

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87
Q

Low/normal levels of Ca, low phosphate, and high Alk phos and PTH are typical labs seen in this condition

A

Rickets/Osteomalacia

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88
Q

Epiphyseal cartilage overgrowth due to inadequate mineralization and failure of chondrocyte maturation is seen in this condition

A

Rickets

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89
Q

Growth plate cartilage and osteoid continues to expand laterally but does not mineralize or mature into bone is seen in this condition

A

Rickets

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90
Q

Skeletal deformation due to lack of structural rigidity is seen in this condition
Windswept deformity, bowing of legs (varus and valgum deformities), Pigeon breast, lumbar lordosis

A

Rickets

91
Q

Condition where radiographs show widening of growth plates and fraying of collagen

A

Rickets

92
Q

Fraying of cartilage as seen on radiograph indicates this condition

A

Rickets

93
Q

Looser zones that are transverse areas of lucency due to microfractures and/or vascular channel erosion are seen on radiograph in this condition

A

Rickets

94
Q

A row of beadlike prominences at the junction of a rib and its cartilage (i.e., enlarged costochondral joints), resembling a rosary, is seen in this condition

A

Rickets

95
Q

Most characteristic diagnostic features of Rickets are seen in this type of bone

A

Long bones
Does still affect bones with intramembranous ossification though (frontal bossing of skull)

96
Q

Vitamin D dependent rickets (type 1) is caused by a deficiency in this

A

1 alpha hydroxylase

97
Q

A deficiency in 1 alpha hydroxylase causes this condition

A

Vitamin D dependent rickets (type 1)

98
Q

Inheritance pattern of Vitamin D dependent rickets (type 1)

A

Autosomal recessive

99
Q

Vitamin D dependent rickets (type 1) involves this gene

A

CYP2R1

100
Q

CYP2R1 gene is involved in this condition

A

Vitamin D dependent rickets (type 1)

101
Q

Type of Rickets where patients develop the condition by age 1 year

A

Vitamin D dependent rickets (type 1)

102
Q

Vitamin D supplements help this type of Rickets

A

Vitamin D dependent rickets (type 1)

103
Q

Type of Rickets caused by VDR mutations (Vit D receptor)

A

Vitamin D dependent rickets (type 2)

104
Q

Mutations in VDR (Vit D receptor) cause this condition

A

Vitamin D dependent rickets (type 2)

105
Q

Inheritance pattern of Vitamin D dependent rickets (type 2)

A

Autosomal recessive

106
Q

Type of Rickets where patients develop the condition in adolescence usually

A

Vitamin D dependent rickets (type 2)

107
Q

When do patients with Vitamin D dependent rickets (type 2) develop the condition?

A

In adolescence usually

108
Q

When do patients with Vitamin D dependent rickets (type 1) develop the condition?

A

By age 1 year

109
Q

IV calcium helps this type of Rickets

A

Vitamin D dependent rickets (type 2)

110
Q

Type of Rickets caused by PHEX mutation on X chromosome

A

X-linked hypophosphatemia (Vit D resistant Rickets)

111
Q

PHEX mutation on the X chromosome causes this condition

A

X-linked hypophosphatemia (Vit D resistant Rickets)

112
Q

What are the levels of Ca and phosphate in X-linked hypophosphatemia (Vit D resistant Rickets)?

A

Normal/high Ca
VERY LOW phosphate

113
Q

What are the levels of Alk Phos and PTH in X-linked hypophosphatemia (Vit D resistant Rickets)?

A

HIGH alk phos
normal PTH

114
Q

What is the effect of X-linked hypophosphatemia (Vit D resistant Rickets) on males?

A

Early rickets

115
Q

What is the effect of X-linked hypophosphatemia (Vit D resistant Rickets) on females?

A

Isoalted hypophosphatemia usually

116
Q

2 supplements used to treat X-linked hypophosphatemia (Vit D resistant Rickets)

A

1,25 dihydroxy vitamin D and phosphate

117
Q

Loss of 1ɑ hydroxylase activity in proximal renal tubules leads to this

A

Chronic renal disease

118
Q

Condition where renal dysfunction leads to loss of phosphate, glucose, bicarbonate, amino acids
Results in renal tubular acidosis (Rickets/osteomalacia)

A

Fanconi syndrome

119
Q

Fanconi syndrome can lead to this condition due to its associated hypophosphatemia

A

Rickets/osteomalacia

120
Q

Condition of inadequate mineralization of bone in remodeling of mature skeleton due to low Vitamin D

A

Osteomalacia

121
Q

Areas of overgrowth in weak bones are seen in Rickets or Osteomalacia?

A

Rickets

122
Q

Morphological widening of osteoid seams (gap between new collagen and zone of mineralization) is seen in this condition

A

Osteomalacia

123
Q

This condition causes excess production of PTH resulting in excess bone resorption

A

Hyperparathyroidism

124
Q

Hyperparathyroidism causes excess production of this, resulting in excess bone resorption

A

PTH

125
Q

Type of Hyperparathyroidism due to autonomous (neoplastic) secretion

A

Primary

126
Q

Type of neoplasm that most commonly causes primary Hyperparathyroidism

A

Parathyroid adenoma

127
Q

Levels of calcium in Primary Hyperparathyroidism

A

High

128
Q

Type of Hyperparathyroidism that is a response to renal loss of calcium in chronic renal disease

A

Secondary

129
Q

Levels of calcium in Secondary Hyperparathyroidism

A

Low
Low Ca leads to high PTH, which compensates and causes normalish Ca

130
Q

Type of Hyperparathyroidism that is a secondary form which has become autonomous

A

Tertiary

131
Q

Level of alk phos in Hyperparathyroidism

A

High

132
Q

Brown tumors of bone are complications of this condition

A

Hyperparathyroidism

133
Q

Microfractures resulting in reactive hypervascularity, hemorrhage and fibrosis and osteoclast accumulation

A

Brown tumors
Seen in Hyperparathyroidism

134
Q

Osteoporosis with cystic change
Form brown tumors (due to hemosiderin)
Seen in Hyperparathyroidism

A

Osteitis Fibrosa Cystica

135
Q

Osteitis Fibrosa Cystica is a complication of this condition

A

Hyperparathyroidism

136
Q

Constellation of skeletal changes due to chronic renal failure

A

Renal Osteodystrophy

137
Q

Secondary hyperparathyroidism, osteopenia/osteoporosis, and osteomalacia are changes due to chronic renal failure seen in this condition

A

Renal Osteodystrophy

138
Q

How does secondary hyperparathyroidism occur due to renal failure in Renal Osteodystrophy?

A
  1. renal Ca loss secondary to tubular dysfunction
  2. compensatory PTH secretion
  3. Ca/P resorbed from bone = fibrosis and cyst formation (Osteitis Fibrosa Cystica)
139
Q

How does Osteopenia/osteoporosis result from chronic renal failure in Renal Osteodystrophy?

A

1 of 3 ways:
1. high PTH
2. renal Ca loss
3. renal tubules don’t excrete H+ (= metabolic acidosis = Ca is resorbed as a buffer)
Generalized loss of Ca from bone

140
Q

How does Osteomalacia result from Renal Osteodystrophy?

A

Renal failure results in inability to convert inactive Vitamin D to active 1,25 Vitamin D form
(leads to inability to mineralize osteoid)

141
Q

Condition characterized by increased, but dysfunctional, bone mass due to increased osteoclast activity and osteoblast response

A

Paget disease

142
Q

Condition where morphology shows bone resorption with increased numbers of large, multinucleated osteoclasts

A

Paget disease

143
Q

Condition characterized by bone deposition without remodeling

A

Paget disease

144
Q

Condition characterized by thick lamellar bone with prominent cement lines

A

Paget disease

145
Q

Thick lamellar bone with prominent cement lines are seen in this condition

A

Paget disease

146
Q

Mosaic pattern of lamellar bone is seen in this condition

A

Paget disease

147
Q

Morphology of Paget disease involves increased numbers of this cell type with increased numbers of nuclei

A

Osteoclasts

148
Q

Do osteoblasts or osteoclasts initially have increased activity in Paget disease?

A

Osteoclasts
Then compensatory increase of osteoblast activity

149
Q

Condition that may initially be due to osteoclastic viral infection or increased RANK or NFk-B activity

A

Paget disease

150
Q

Condition characterized by the following 3 phases:
Osteolytic, Mixed osteoclastic-osteoblastic, osteosclerotic

A

Paget disease

151
Q

Condition involving:
1. increased osteoclast activity and bone resorption
2. compensatory increased osteoblast activity and bone deposition
3. burnt out osteoclasts with continued bone deposition by osteoblasts

A

Paget Disease

152
Q

In Paget disease, there is increased bone density with no remodeling, leading to this type of bone

A

Weaker woven bone

153
Q

Radiographs showing thickened cortices, cotton wool appearance and bowing of weight bearing bones is seen in this condition

A

Paget disease

154
Q

Cotton wool appearance of bones seen radiographically are characteristic of this condition

A

Paget disease

155
Q

A patient with a history of increasing hat size or hearing loss may have this condition

A

Paget disease

156
Q

Paget disease is relatively common in these populations

A

European/Anglo

157
Q

Bone enlargement and weakness are seen in this condition
Also bowing of weight bearing bones and compression of nerve roots or cranial contents
(skull, femur, axial skeleton are common sites)

A

Paget disease

158
Q

Levels of Alk phos in Paget disease

A

Elevated

159
Q

Levels of Ca and P in Paget disease

A

Both normal

160
Q

Osteosarcoma and Osteoblastic hypermetabolic state are complications of this condition

A

Paget disease

161
Q

Complication of Paget disease due to increased blood flow requirement causing increased demand on heart
Exacerbates heart disease and may produce high output cardiac failure in extensive disease

A

Osteoblastic hypermetabolic state

162
Q

This condition may exacerbate heart disease and produce high output cardiac failure in extensive disease

A

Paget disease

163
Q

Rupture of blood vessels forms this during healing of a fracture

A

Hematoma

164
Q

In the healing of a fracture, formation of granulation tissue produces this scaffold

A

Fibrin scaffold
Fibroblasts, WBCs, capillaries grow into hematoma

165
Q

During fracture healing, osteoid is deposited similar to this type of ossification during the formation of soft callus

A

Intramembranous

166
Q

During fracture healing, chondroid matrix is ossified similar to this type of ossification during the formation of soft callus

A

Endochondral

167
Q

This is the final stage of fracture healing

A

Remodeling

168
Q

Why is resumption of weight bearing so critical during healing of fractures?

A

Non-stressed parts of callus are resorbed
Stressed parts of callus are remodeled to new lamellar bone
Physical stress on bone helps bone remodel to produce new bone

169
Q

In a fracture with non-union, ingrowth of synovium may produce this

A

Pseudoarthrosis

170
Q

Type of fracture:
Overlying skin is intact

A

Simple (closed)

171
Q

Type of fracture:
Bone communicates with skin surface
Risk of osteomyelitis

A

Compound (open)

172
Q

Type of fracture:
Bone is fragmented

A

Comminuted

173
Q

Type of fracture:
Fracture along long axis
Associated with torsional injuries

A

Spiral

174
Q

Type of fracture:
Fracture due to axial load

A

Compression (impacted)

175
Q

Type of fracture:
Fracture perpendicular to long axis

A

Transverse

176
Q

Type of fracture:
Tendinous insertion pulled off bone

A

Avulsion

177
Q

Type of fracture:
Ends of bone are not aligned

A

Displaced

178
Q

Type of fracture:
Slow developing fracture due to repeated trauma and microfractures

A

Stress

179
Q

Type of fracture:
Fracture extends partially through bone
Mostly in pediatrics

A

Greenstick

180
Q

Why is it called a Greenstick fracture?

A

Fracture extends partially through bone
Like a green twig - bends but does not break through full thickness

181
Q

Type of fracture:
Fracture of bone weakened by underlying bone disease

A

Pathologic

182
Q

Infarction of bone and marrow

A

Avascular necrosis
Aka Osteonecrosis

183
Q

What is the most common site of Avascular necrosis?

A

Femoral head

184
Q

Avascular necrosis resolves with this, resulting in dense bone seen on radiology

A

Ingrowth of new bone

185
Q

Avascular necrosis is repaired by this

A

Creeping substitution

186
Q

Condition with empty lacunae, bone that often appears denser, and subchondral linear lucency later

A

Avascular necrosis

187
Q

How does bone appear in Avascular necrosis?

A

Often appears denser
Subchondral linear lucency later

188
Q

Idiopathic avascular necrosis of femoral head epiphysis

A

Legg-Calve-Perthes Disease

189
Q

Who is more likely to have Legg-Calve-Perthes Disease, male or female?

A

Male, 4:1

190
Q

What does a patient with Legg-Calve-Perthes Disease present with?

A

Limp +/- pain
Pain often present at thigh or knee

191
Q

What is the treatment for Legg-Calve-Perthes Disease?

A

Leg immobilization
Allows remineralization so that femoral head heals to conform to shape of acetabulum

192
Q

Legg-Calve-Perthes Disease is idiopathic avascular necrosis of this

A

Femoral head epiphysis

193
Q

Legg-Calve-Perthes Disease is uncertain etiology of this

A

Avascular necrosis

194
Q

Infection of bone and bone marrow

A

Osteomyelitis

195
Q

2 routes by which Osteomyelitis may occur

A

Hematogenous
Direct extension or traumatic implantation

196
Q

This is the most common route of Osteomyelitis in pediatrics

A

Hematogenous

197
Q

This is the most common location of Osteomyelitis in pediatrics

A

Metaphysis (due to slowing of circulation)

198
Q

Most common organism that causes Osteomyelitis in pediatrics

A

S. aureus

199
Q

Direct extension causing Osteomyelitis in pediatrics may occur with these 2 things

A

Otitis, open fractures

200
Q

Most common route of Osteomyelitis in adults

A

Direct extension

201
Q

Hematogenous route of Osteomyelitis in adults tends to occur in this part of the body

A

Vertebra (bodies)

202
Q

Most common organism that causes Osteomyelitis in all populations

A

S. aureus

203
Q

Common organism that causes Osteomyelitis in IV drug users

A

S. aures

204
Q

Common organism that causes Osteomyelitis in Sickle Cell anemia

A

Salmonella

205
Q

Salmonella can cause Osteomyelitis in patients with this

A

Sickle Cell anemia

206
Q

3 Common organisms that cause Osteomyelitis in UTI/GI

A

E. coli
Pseudomonas
Klebsiella

207
Q

Common organism that causes Osteomyelitis in Potts disease

A

M. tuberculosis involvement of vertebra

208
Q

M. tuberculosis involvement of vertebra is a common cause of Osteomyelitis in patients with this

A

Potts disease

209
Q

Necrotic focus of infected bone as seen in Osteomyelitis

A

Sequestrum

210
Q

Sclerotic reactive bone that surrounds sequestrum, as seen in Osteomyelitis

A

Involucrum

211
Q

Complication of Osteomyelitis that is a persistent infection in an involucrum

A

Brodie Abscess

212
Q

Brodie Abscess is a persistent infection in an involucrum and is a complication of this

A

Osteomyelitis

213
Q

Condition where radiology may show lucency with surrounding sclerosis or dense central nidus

A

Osteomyelitis

214
Q

This may become Chronic Osteomyelitis
Due to inadequate antibiotic duration or type, inadequate debridement, delayed diagnosis

A

Pyogenic Osteomyelitis

215
Q

Brodie abscess/sequestrum may form and recur, sometimes decades later, from this condition

A

Chronic Osteomyelitis

216
Q

Draining sinuses, AA amyloidosis, and malignancy are complications of this

A

Chronic Osteomyelitis

217
Q

AA amyloidosis is a complication of this condition

A

Chronic Osteomyelitis

218
Q

This is the most common, classic location for Tuberculosis Osteomyelitis

A

Vertebral bodies

219
Q

This condition is more destructive and difficult to eradicate that pyogenic osteomyelitis

A

Tuberculosis Osteomyelitis

220
Q

Type of Osteomyelitis established by metastatic spread, usually from lung

A

Tuberculosis Osteomyelitis

221
Q

Long term infection with Osteomyelitis may result in malignancy, such as this

A

Squamous cell carcinoma of draining sinus tract

222
Q

Squamous cell carcinoma of draining sinus tract is a malignancy that can be a complication of this condition

A

Chronic Osteomyelitis

223
Q

Potts disease is another name for this

A

Tuberculosis Osteomyelitis

Skin & MSK (30 decks)

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