Infectious Diseases of Skin and MSK - Fungi and Parasites Flashcards
Type of fungal infection that begins in cornified (horny) layer of skin and spreads outward
Often called ringworm or tineas
Cutaneous
Fungal species that causes White piedra
Affects the hairs of the groin and axillae
Trichosporon
Does Trichosporon cause White or Black piedra?
White
Trichosporon species causes this condition that affects the hairs of the groin and axillae
White Piedra
Fungal species that causes Black piedra
Affects the hair of the scalp
Piedraia hortae
Piedraia hortae causes this condition that affects the hair of the scalp
Black piedra
Does Piedraia hortae cause White or Black Piedra?
Black piedra
Lipophilic yeast that is part of the normal flora
Malassezia furfur
Fungus that has histological spaghetti and meatballs appearance
Malassezia furfur
What is the treatment for Malassezia furfur?
Ketoconazole
Black fungus that causes tinea nigra
Appears dematiaceous and frequently branched with septate hyphae
Found in tropical and subtropical regions
Hortaea werneckii
Hortaea werneckii causes this condition
Tinea nigra
Typical lesion of these is an annular or serpentine scaling patch with raised margin
Dermatophytes
Dermatophyte infection of nails
Onychomycosis
Dermatophytes (ringworm) should be cultured on this agar
Sabouraud’s agar
These can be observed with a “woods lamp” (a UV light)
Dermatophytes
What is the treatment for dermatophytes (ringworm)?
Topical keratolytic agents with terbinafine
What is the treatment for Candida albicans?
Miconazole
Thermally dimorphic fungus
Nodular and ulcerative lesions at the site of inoculation
Spreads along the draining lymphatics
1 week to 6 months post inoculation secondary nodules appear along the lymph tract
Sporothrix schenckii
What is the treatment for Sporothrix schenckii?
Itraconazole (or fluconazole)
Chronic infection with melanized fungi
Is disfiguring
Chromoblastomycosis
What is the treatment for Chromoblastomycosis?
Itraconazole
Condition referred to as “kala-azar”, has liver and spleen involvement
Visceral leishmaniasis
Leishmaniasis invades this type of cells
Mononuclear phagocyte system cells (macrophages)
What is the natural reservoir of Leishmaniasis?
Rodents and small animals
Leishmaniasis is transmitted by this
Sand fly bite
Parasite that causes insidious progression, and papules become pruritic and may persist for years
Lesions are scarring
Leishmaniasis
This is a late complication of cutaneous Leishmaniasis that affects the upper respiratory passages
Espunda
Espundia is a late complication of cutaneous infection with this parasite
Leishmaniasis
Treatment options for this parasite are fairly toxic and includes sodium stibogluconate, amphotericin B, pentamidine, paromomycin
Leishmaniasis
Nematode that lives in the intestines of dogs and cats
In the skin they cause a creeping lesion called cutaneous larval migrans
Induces bleeding, eosinophilic granulomas, and necrosis
Toxocara
Where does Toxocara live?
Intestines of dogs and cats
This parasite causes a creeping lesion called cutaneous larval migrans
Toxocara
This parasite induces bleeding, eosinophilic granulomas, and necrosis
Toxocara
Parasite that is a dog and cat hookworm
Ancylostoma braziliense
Parasite where filariform larvae penetrate the skin but cannot develop further, causing cutaneous larval migrans (also called ground itch and creeping eruption)
Larvae wander, creating serpentine tunnels
Ancylostoma braziliense
This is the treatment for Ancylostoma braziliense
Albendazole (or ivermectin)
Parasitic nematode that causes Trichinosis
Trichinella spiralis
Parasite that lives in the mucosa of the duodenum and jejunum
Trichinella spiralis
Where does Trichinella spiralis live?
Mucosa of the duodenum and jejunum
Parasite that is transmitted by ingestion of contaminated meats, particularly pork
Trichinella spiralis
Parasite that exists in a larvae form within nurse cells
Trichinella spiralis
Humans are dead end hosts for this parasite
Larvae will die and calcify
Trichinella spiralis
Initial symptoms of this parasite consist of nonspecific abdominal and flu-like complaints
Trichinella spiralis
Parasite that causes influenza-like symptoms, periorbital edema, and “splinter” hemorrhages beneath the nails
Trichinella spiralis
Treatment of Trichinella spiralis during the GI phase consists of this drug
Albendazole
Tissue invading parasite that causes dracontiasis
Dracunculus medinensis (Guinea worm)
Dracunculus medinensis (Guinea worm) requires this environment
Freshwater
Infection with this parasite forms an ulcer and releases larvae when exposed to water
Typically a burning blister appears suddenly, which feels better when immersed in water
Dracunculus medinensis (Guinea worm)
Cestode that is a pork tapeworm
Taenia solium
Cysticercosis is caused by this parasite
Taenia solium
Does this describe Trichinosis or Cysticercosis:
Transmitted by ingestion of infected meat from pigs or wild game
Trichinosis
Does this describe Trichinosis or Cysticercosis:
Transmitted by fecal-oral from someone infected
Cysticercosis
Does this describe Trichinosis or Cysticercosis:
Found worldwide
Trichinosis
Does this describe Trichinosis or Cysticercosis:
Found mainly in Mexico, central and south America, Philippines, southeast Asia
Cysticercosis
Does this describe Trichinosis or Cysticercosis:
Flue-like symptoms and periorbital swelling
Trichinosis
Does this describe Trichinosis or Cysticercosis:
Nurse cells develop 2-4 weeks after ingestion of infected meat
Can remain viable for decades before calcifying
Trichinosis
Does this describe Trichinosis or Cysticercosis:
Minimal symptoms restricted to skeletal muscle
Cysticercosis
Does this describe Trichinosis or Cysticercosis:
Cysts develop 3-4 months after ingestion of eggs and remain viable for up to 5 years before calcifying
Cysticercosis
Does this describe Trichinosis or Cysticercosis:
x-ray unlikely to show calcifications for decades
Trichinosis
Does this describe Trichinosis or Cysticercosis:
x-ray shows cigar-shaped cysts found while looking for something else
Cysticercosis
Fleas or lice: live off, leap on to feed
Fleas
Fleas or lice: Live on, may rub off
Lice
Pubic lice is caused by this species
Pediculosis pubis
Treatment for pubic lice
Permethrin 1% cream
Vector for Lyme disease and Babesia
Ixodes (hard tick)
Genus within Ixodes that is the vector for RMSF
Dermacentor (hard tick)
Vector for relapsing fever
Ornithodoros (soft tick)
Human itch mite species that causes scabies
Sarcoptes scabiei var. Hominis
Condition caused by Sarcoptes scabiei var. Hominis that involves intense itching and pimple-like skin rash
Scabies
Treatment for Scabies
Permethrin 5% cream