Sjogren's Syndrome Flashcards

1
Q

What is Sjogren’s syndrome?

A

Autoimmune condition which affects exocrine glands

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2
Q

What does Sjogren’s syndrome lead to symptoms of?

A

Dry mucous membranes eg dry mouth, dry eyes & dry vagina

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3
Q

What is primary Sjogren’s?

A

Where condition occurs in isolation

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4
Q

What is secondary Sjogren’s syndrome?

A

Occurs related to SLE or RA

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5
Q

What auto-antibodies are associated with Sjogren’s syndrome?

A

Anti-Ro

Anti-La

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6
Q

Investigation of Sjogren’s syndrome?

A

Schirmer test

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7
Q

What is Schirmer test?

A
  • Inserting folded piece of filter paper under lower eyelid with strip hanging out over eyelid
  • Leave for 5 mins & distance along strip that becomes moist is measured
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8
Q

How far should tears travel in a healthy adult?

A

15mm

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9
Q

How far is significant for tears not to travel?

A

Less than 10mm

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10
Q

Management of Sjogren’s sydnrome?

A

Artificial tears
Artificial saliva
Vaginal lubricants
Hydroxychloroquine: halts disease progression

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11
Q

Complications of Sjogren’s syndrome?

A
Eye problems (conjunctivitis, corneal ulcers) 
Oral problems (cavities, candida)
Vaginal problems (candidiasis & sex dysfunction)
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