Sjogren's Syndrome Flashcards
1
Q
What is Sjogren’s syndrome?
A
Autoimmune condition which affects exocrine glands
2
Q
What does Sjogren’s syndrome lead to symptoms of?
A
Dry mucous membranes eg dry mouth, dry eyes & dry vagina
3
Q
What is primary Sjogren’s?
A
Where condition occurs in isolation
4
Q
What is secondary Sjogren’s syndrome?
A
Occurs related to SLE or RA
5
Q
What auto-antibodies are associated with Sjogren’s syndrome?
A
Anti-Ro
Anti-La
6
Q
Investigation of Sjogren’s syndrome?
A
Schirmer test
7
Q
What is Schirmer test?
A
- Inserting folded piece of filter paper under lower eyelid with strip hanging out over eyelid
- Leave for 5 mins & distance along strip that becomes moist is measured
8
Q
How far should tears travel in a healthy adult?
A
15mm
9
Q
How far is significant for tears not to travel?
A
Less than 10mm
10
Q
Management of Sjogren’s sydnrome?
A
Artificial tears
Artificial saliva
Vaginal lubricants
Hydroxychloroquine: halts disease progression
11
Q
Complications of Sjogren’s syndrome?
A
Eye problems (conjunctivitis, corneal ulcers) Oral problems (cavities, candida) Vaginal problems (candidiasis & sex dysfunction)
