Psoriatic Arthritis

Question 1

What disease group is PA part of?

Answer 1

Seronegative spondyloarthropathies

Question 2

What is PA?

Answer 2

Inflammatory arthritis assoc with psoriasis

Question 3

Who gets PA?

Answer 3

10-20% of patient’s with psoriasis

-Typically middle aged

Question 4

Patterns of presentation?

Answer 4

• Symmetrical polyarthritis: hands, wrists, ankles, DIP joints
• Asymmetrical pauciurarthritis: mainly digits and feet
• Spondylitic pattern: Back stiffness, saroiliitis, atlanto-axial joiny involvement
• Other area: Spine, achilles, plantar fascia

Question 5

Signs of psoriatic arthritis?

Answer 5

Plaques of psoriasis on skin

• Pitting of nails
• Onycholysis
• Dactylitis
• Enthesitis

Question 6

What is dactylitis?

Answer 6

Finger inflammation

Question 7

Other associated symptoms with psoriatic arthritis?

Answer 7

Eye disease
Aortitis
Amyloidosis

Question 8

Investigation of PA?

Answer 8

-Psoriasis epidemiological screening tool (PEST)

Question 9

X-ray changes in PA?

Answer 9

Periostitis 
Ankylosis 
Osteolysis 
Dactylitis 
Pencil in cup

Question 10

What is periostitis?

Answer 10

Periosteum inflammation

Question 11

What is ankylosis?

Answer 11

Bones joining together= joint stiffening

Question 12

What is osetolysis?

Answer 12

Bone destruction

Question 13

What is most severe form of psoriatic arthritis?

Answer 13

Arthritis mutilans

Question 14

What does arthritis Mutilans lead to?

Answer 14

Telescopic finger

Question 15

Management of PA?

Answer 15

NSAIDs for pain
DMARDs
Anti-TNF meds
Ustekinumab (LAST LINE)