simvastatin Flashcards

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1
Q

What are the common indications for Simvastatin?
Simvastatin is commonly used to treat hypercholesterolemia (high cholesterol) and to reduce the risk of cardiovascular events.

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2
Q

What is the normal dose of Simvastatin?
The normal dose of Simvastatin is 10-40mg once daily, depending on the patient’s condition.

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3
Q

Is there an initial dose for Simvastatin?
The initial dose of Simvastatin is usually 10-20mg once daily, depending on the patient’s condition.

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4
Q

What drug class does Simvastatin belong to?
Simvastatin belongs to the class of drugs called HMG-CoA reductase inhibitors, also known as statins.

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5
Q

What possible optimization issues should pharmacists lookout for when patients take Simvastatin?
Pharmacists should lookout for potential drug interactions, especially with medications such as clarithromycin and verapamil. They should also monitor for signs of myopathy (muscle pain or weakness) and liver dysfunction.

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6
Q

What is the maintenance dose of Simvastatin?
The maintenance dose of Simvastatin is the same as the normal dose, which is 10-40mg once daily, depending on the patient’s condition.

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7
Q

Is Simvastatin recommended during pregnancy?
Simvastatin is not recommended during pregnancy. Pregnant women with hypercholesterolemia should be managed with other medications.

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8
Q

How should patients take Simvastatin?
Patients should take Simvastatin as directed by their healthcare provider. The tablet should be taken orally, with or without food, usually in the evening. Patients should also avoid drinking grapefruit juice while taking Simvastatin, as this may increase the risk of side effects.

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