sildenafil Flashcards

1
Q

What are the common indications for Sildenafil?
Sildenafil is commonly used to treat erectile dysfunction (ED) and pulmonary arterial hypertension (PAH).

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2
Q

What is the normal dose of Sildenafil?
The normal dose of Sildenafil for ED is 50mg, taken as needed, about 1 hour before sexual activity. The dose may be adjusted based on the patient’s response and tolerability.
The normal dose of Sildenafil for PAH is 20mg, taken three times daily, with or without food. The dose may be adjusted based on the patient’s response and tolerability.

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3
Q

Is there an initial dose for Sildenafil?
The initial dose of Sildenafil for ED is 50mg, taken as needed, about 1 hour before sexual activity. The dose may be adjusted based on the patient’s response and tolerability.
The initial dose of Sildenafil for PAH is 20mg, taken three times daily, with or without food. The dose may be adjusted based on the patient’s response and tolerability.

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4
Q

What drug class does Sildenafil belong to?
Sildenafil belongs to the class of drugs called phosphodiesterase type 5 (PDE5) inhibitors.

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5
Q

What possible optimization issues should pharmacists lookout for when patients take Sildenafil?
Pharmacists should lookout for potential drug interactions, especially with medications such as nitrates and alpha-blockers. They should also monitor for signs of hypotension (low blood pressure) and priapism (prolonged erection).

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6
Q

What is the maintenance dose of Sildenafil?
The maintenance dose of Sildenafil varies depending on the patient’s condition and the indication.

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7
Q

Is Sildenafil recommended during pregnancy?
Sildenafil is not recommended during pregnancy. Pregnant women with PAH should be managed with other medications.

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8
Q

How should patients take Sildenafil?
Patients should take Sildenafil as directed by their healthcare provider. The tablet should be taken orally, with or without food, about 1 hour before sexual activity for ED or three times daily for PAH. Patients should also avoid taking Sildenafil with nitrates or alpha-blockers and should seek medical attention if they experience chest pain or a prolonged erection.

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