5-FLOUROURACIL Flashcards
What is the common indication for 5-Fluorouracil?
Answer: 5-Fluorouracil is commonly used to treat various types of cancer, including breast, colorectal, gastric, and pancreatic cancer.
What is the normal maintenance dose for 5-Fluorouracil?
Answer: The normal maintenance dose for 5-Fluorouracil is usually 300-500 mg/m2/day, given by continuous infusion over several days.
What are the possible optimization issues when taking 5-Fluorouracil?
Answer: Possible optimization issues with 5-Fluorouracil include toxicity, which can occur due to the narrow therapeutic index of the drug, and the need for dose adjustments based on individual patient factors such as age, weight, and kidney function.
What should pharmacists lookout for when patients take 5-Fluorouracil?
Answer: Pharmacists should be aware of potential drug interactions with other medications that may affect 5-Fluorouracil metabolism, monitor patients for signs of toxicity, and counsel patients on the importance of adhering to the dosing schedule.
What is the normal initial dose for 5-Fluorouracil?
Answer: The normal initial dose for 5-Fluorouracil depends on the specific cancer being treated and the patient’s individual factors. The dose may range from 300 to 1000 mg/m2/day, given by infusion over several days.
