DULOXETINE Flashcards

1
Q

8What is the common indication for Duloxetine?
Answer: Duloxetine is commonly used to treat depression, anxiety disorders, and chronic pain conditions such as fibromyalgia and neuropathic pain.

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2
Q

What is the normal maintenance dose for Duloxetine?
Answer: The normal maintenance dose for Duloxetine ranges from 60 to 120 mg per day.

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3
Q

What is the drug class of Duloxetine?
Answer: Duloxetine belongs to the class of drugs known as serotonin-norepinephrine reuptake inhibitors (SNRIs).

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4
Q

What are the possible optimization issues when taking Duloxetine?
Answer: Possible optimization issues with Duloxetine include the risk of adverse effects such as nausea, dry mouth, and sexual dysfunction. Dose adjustments may also be necessary based on individual patient factors such as age, weight, and liver function.

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5
Q

What are the common side effects of Duloxetine?
Answer: Common side effects of Duloxetine include nausea, dry mouth, dizziness, and insomnia. It can also cause increased blood pressure, sweating, and sexual dysfunction.

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6
Q

What should pharmacists lookout for when patients take Duloxetine?
Answer: Pharmacists should monitor patients for signs of adverse reactions such as suicidal thoughts, hyponatremia, and serotonin syndrome. They should also be aware of potential drug interactions and counsel patients on the importance of adhering to the dosing schedule.

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7
Q

State the dose of Duloxetine indicated for Major depressive disoreder

A

60mg once daily

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8
Q

State the dose of duloxetine in GAD?

A

Initial 30mg once daily increase if necessary to 60mg OD max 120mg OD

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9
Q

Avoid Duloxetine is egfr is less than?

A

30ml/L

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