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HRM > Simple Female Repro Drugs > Flashcards

Simple Female Repro Drugs Flashcards

1
Q

How do you promote folliculogenesis in women with hypothalamic anovulatory function?

A

FSH and LH with daily injection

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2
Q

How do you achieve super ovulation in normal ovulatory women?

A

FSH/LH on d 2-3 of menstrual cycle

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3
Q

What are the urinary derived gonadotropins?

A

Menotropin and urofolitropin. (gonadoTROPIN and these are TROPINs)

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4
Q

What ar ethe recombinant human gonadotropins?

A

Follitropin a and follitropin b

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5
Q

What SERM is an antagonist or the estrogen receptor in the hypothalamus?

A

Clomiphene Citrate (multiple fetuses are possible)

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6
Q

What is the GnRH analog?

A

Leuprolide can be used in lieu of GnRH. Nonpulsatile will shut down pituitary

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7
Q

GnRH Antagonist?

A

Cetrorelix, Ganirelix (relix will make your testes/ovary relax)

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8
Q

SERM that is antagonist in Breast, Vasculature and agonist in uterus, bone, lipoproteins?

A

Tamoxifen (has a risk of uterine cancer)

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9
Q

Pure estrogen antaonist?

A

Fulvestrant. Used for estrogen receptive breast cancer

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10
Q

SERM that is agonist in bone and lipoproteins but antagonist in breast and uterus?

A

Raloxifene (used in uterine cancer b/c antagonist)

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11
Q

SERM that is antagonist in breast and no other known effects?

A

Toremifene (2remifene as in 2 breasts that are being antagonized)

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12
Q

Steriodal aromatase inhibitor? Is it reversible?

A

Exemestane is steroid, so it is nonreversible

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13
Q

Nonsteroidal aromatase inhibitor? Is it reversible?

A

Anastrozole and letrozole. Nonsteroidal, reversible (end in zole so block steroid synth like azoles do in antifungals)

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14
Q

Synthetic progestane?

A

Medroxyprogestreone acetate

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15
Q

Synthetic estrane?

A

Norethindrone

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16
Q

Synthetic gonane?

A

Levonorgestrel. Potent at low dose

17
Q

Progesterone antagonist for either emergency contraception or terminating early pregnancy?

A

Mifepristone: emergency contraceptive at small dose or larger dose to terminate early preggers. Use Mif if you screwed up and you don’t want her to become a Milf

18
Q

Progesterone antagonist for emergency contraception?

A

Ulipristal acetate for emergency contraception as it delays ovulation and alters endometreium.

HRM (40 decks)

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