KC's diabetes overview; 3.18/19

Question 1

What antibodies are often present with DMI?

Answer 1

Glutamic Acid Decarboxylase (GAD)-65 antibodies

Question 2

How is gestational DM diagnosed?

Answer 2

Glucose tolerance test (1hr challenge. If failed, then 3 hour test checking qhr…2 high reads = gestational DM)

Question 3

There are lots of drugs that can cause hyperglycemia…here are some of them:

Answer 3

Glucocorticoids
Oral contraceptives
Cyclosporine, tracrolimus, sirolimus
Niacin
HIV protease inhibitors
Thiazide diuretics
Statins
GnRH agonists

Question 4

Who should be screened for diabetes?

Answer 4

Adults with BMI > 25 and one or more risk factors

Question 5

What are some risk factors associated with diabetes?

Answer 5

Physical inactivity
Relative with DM
HTN, HDL, elevated TGs
Others

Question 6

What is the usual goal HA1c with diabetes (measured every 6 months)?

Answer 6

Less than 7-8%

Question 7

When would a goal HA1c be less than the normal 7-8%?

Answer 7

Short disease duration
Long life expectancy
No significant CVD

Question 8

When would it be ok for the HA1c goal to be higher than the normal 7-8%?

Answer 8

Severe hypoglycemia
Limited life expectancy
Advanced complications
Extensive comorbid conditions
Those who just can't meet other targets

Question 9

Other than HA1c, what else should be checked/avoided in diabetes patients?

Answer 9

LDL (annually)
BP
Proteinuria screen (annually)
Flu shot (annually)
Pneumococcal vaccine (UTD)
No tobacco
TGs (annually)

Question 10

What is the goal LDL level in a diabetic?

Answer 10

<100mg/dL (high dose statin if otherwise)

Question 11

What is the goal BP in a diabetic?

Answer 11

<140/80mmHg

Question 12

What is the goal for fasting TG level? Non-fasting?

Answer 12

<180mg/dL