Signs Flashcards

1
Q

Kussmaul’s respiration?

A

DKA, hyperkalemia

(= hyperventilation)

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2
Q

Trousseau’s sign?

A

hypoparathyroidism, hypocalcemia

(= inflation of BP cuff above systolic pressure induces hand spasm)

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3
Q

Chvostek’s sign?

A

hypoparathyroidism, hypocalcemia

(= tap over facial nerve + look for spasm of facial muscles)

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4
Q

Beck’s triad?

A

pericardial effusion

(= falling BP, rising JVP, muffled heart sounds)

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5
Q

Quincke’s sign?

A

aortic regurgitation

(= capillary pulsation in nail beds)

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6
Q

De Musset’s sign?

A

aortic regurgitation

(= head nodding with each heartbeat)

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7
Q

Traube’s sign?

A

aortic regurgitation

(= pistol-shot sound when auscultating femoral artery)

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8
Q

malar flush?

A

mitral stenosis, SLE

(= pink patches on cheeks)

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9
Q

erythema marginatum?

A

rheumatic fever

(= redness of torso + inner limbs)

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10
Q

machinery murmur?

A

patent ductus arteriosus

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11
Q

clubbed blue toes with pink non-clubbed fingers?

A

patent ductus arteriosus

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12
Q

“hair on-end” X-ray?

A

beta thalassaemia

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13
Q

pain at McBurney’s point?

A

appendicitis

(= 2/3 away from umbilicus to ASIS)

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14
Q

fetor hepaticus?

A

liver failure

(= breath smells of rotten eggs)

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15
Q

Dupuytren’s contracture?

A

DM, liver failure

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16
Q

xanthelasma?

A

liver cirrhosis, DM

(= yellow fat deposits under skin around eyes)

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17
Q

liver flap/asterixis?

A

hepatic encephalopathy

(= flapping tremor with wrist extended)

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18
Q

Courvoisier’s sign?

A

if a patient with an enlarged gallbladder has painless jaundice, they don’t have gallstones

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19
Q

Murphy’s sign?

A

acute cholecystitis

(= pain on taking a deep breath when examiner places 2 fingers on RUQ)

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20
Q

Cullen’s sign?

A

acute pancreatitis

(= periumbilical bruising)

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21
Q

Grey Turner’s sign?

A

acute pancreatitis

(= left flank bruising)

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22
Q

Kayser-Fleischer ring?

A

Wilson’s disease

(= green-brown pigment in cornea)

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23
Q

PIZZ phenotype?

A

alpha-1 antitrypsin deficiency

(SOB from emphysema, cirrhosis, cholestatic jaundice)

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24
Q

Heberden’s nodes?

A

osteoarthritis

(= bone swellings at DIPJs)

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25
Bouchard's nodes?
osteoarthritis (= bone swellings at PIPJs)
26
ulnar deviation?
rheumatoid arthritis (= fingers deviate towards the ulnar side of the wrist)
27
swan neck (/Z thumb)?
rheumatoid arthritis (= hyperextension of PIPJ + flexion of DIPJ)
28
Boutonniere deformity?
rheumatoid arthritis (= flexion of PIPJ + hyperextension of DIPJ)
29
hammer toe deformity?
rheumatoid arthritis (= 2nd/3rd/4th toe is bent at the middle joint so it resembles a hammer)
30
bamboo spine?
ankylosing spondylitis (= fusion of spinous processes)
31
"telescopic fingers"?
psoriatic arthritis (= bone shortening)
32
"pencil in cup" on X-ray?
psoriatic arthritis
33
Gottron's papules?
dermatomyositis (= scaly erythmatosus plaques over knuckles)
34
heliotrope eyelids?
dermatomyositis (= purple eyelids)
35
"sunburst" appearance on X-ray?
osteosarcoma (- soft tissue calcification)
36
Brudzinski's sign?
meningitis + SAH (= severe neck stiffness causes the patient's hips + knees to flex when the neck is flexed)
37
Kernig's sign?
meningitis, SAH (= pain/resistance with passive extension of the knee)
38
psoas sign?
appendicitis (= RIF pain on right hip flexion)
39
Rosvig's sign?
appendicitis (= palpation of LIF causes pain in RIF)
40
obturator sign?
appendicitis (= RIF pain on right hip flexion + internal rotation)
41
Babinski's sign?
UMN lesion (= stimulation of the lateral plantar aspect of the foot causes dorsiflexion of big toe; causes plantar flexion in health)
42
frothy urine?
protein in urine (e.g. nephrotic syndrome)
43
"bag of worms" in scrotum?
varicoele (= distended scrotal blood vessels)
44
bright white lemon-shape on CT?
extradural (/epidural) haemorrhage
45
dark sickle-shape on 1 hemisphere on CT?
subdural haemorrhage
46
bright white spherical shape on CT?
intracerebral haemorrhage
47
white star-shape on CT?
subarachnoid haemorrhage (SAH)
48
non-blanching petechial/purpuric rash?
meningitis
49
oligoclonal IgG bands on CSF examination?
multiple sclerosis
50
describe the parkinsonian gait
stooped posture, small steps, reduced arm swinging
51
>35 CAG repeats on genetic testing?
Huntington's disease
52
Jacksonian march?
focal epilepsy (in frontal lobe) (= seizure "marches" up/down motor homunculus from face/thumb)
53
anti-AChR + anti-MUSK?
myasthenia gravis
54
anti-P/Q type VGCC Ab?
lambert eaton syndrome
55
wrist drop?
radial nerve (C5-T1) palsy
56
claw hand?
ulnar nerve (C7-T1) palsy
57
foot drop?
sciatic nerve (L4-S3) palsy (specifically the common peroneal branch)
58
flaccid paralysis?
LMN lesion (= floppy)
59
spastic paralysis?
UMN lesion (= tense)
60
"inverted champagne bottle" appearance of legs?
charcot-marie-tooth syndrome (CMT) (= due to peroneal muscle atrophy of legs)
61
Gower's sign?
Duchenne muscular dystrophy (DMD) (= child uses hands on their legs to help them stand up; due to proximal muscle weakness in pelvis)
62
productive cough with khaki sputum?
bronchiectasis
63
"ground glass" appearance on HRCT of thorax?
interstitial lung disease (ILD)
64
lupus pernio?
sarcoidosis (= raised, purple skin lesions on cheeks + nose)
65
crescentic glomeruli on kidney biopsy?
Goodpasture's syndrome
66
"thumb sign" on lateral X-ray of neck?
acute epiglottitis
67
"barking" cough?
croup
68
periorbital purpura (/"panda eyes")?
amyloidosis
69
"cobblestone" appearance of skin?
lymphoedema
70
Stemmer's sign?
lymphoedema (= skin at the bottom of the 2nd toe or middle finger can't be pinched)
71
Whirlpool sign?
ovarian torsion (= twisted vascular pedicle of ovaries)
72
villous atrophy + crypt hyperplasia?
Coeliac disease
73
what is Saint's triad?
hiatus hernia, cholelithiasis, colonic diverticulosis
74
what is Reiter's triad?
conjunctivitis, urethritis, arthritis (reactive arthritis; "can't see, can't wee, can't climb a tree"
75
pelvic/perineal pain lasting >3 months?
chronic prostatitis (RFx: Trauma causing nerve damage in lower urinary tract)
76
what is Charcot's triad?
fever, RUQ pain, jaundice (ascending cholangitis)
77
low calcium, high phosphate, high uric acid, high potassium?
tumour lysis syndrome
78
spiral-shaped, gram -ve bacteria?
H.pylori
79
Tennis elbow?
lateral epicondylitis
80
Golfer's elbow?
medial epicondylitis
81
CXR: "barrel chest", flattened hemidiaphragm, cardiomegaly?
COPD
82
raised serum ACE + calcium?
sarcoidosis
83
SLE w/ skin involvement?
discoid lupus erythematosus
84
HLA-DR7?
antiphospholipid syndrome
85
HLA_DR2?
SLE
86
HLA-DR8?
ankylosing spondylitis
87
HLA-B27?
SpA
88
HLA-DR3?
Grave's
89
HLA-DQ2, HLA-DQ8?
coeliac
90
HLA-DR4, HLA-DR5?
RA
91
CA-125?
ovarian cancer (remember by "2" ovaries)
92
CA-19,9?
pancreatic cancer (or oesophagus or bile ducts)
93
CEA?
colorectal cancer ("CEA" looks like "caecum")
94
HER-2?
breast cancer
95
BRCA?
breast cancer
96
AFP?
liver cancer non-seminoma testicular cancer
97
Burning sensation whilst showering, tingling in hands + feet, + optic neuritis. What is the most likely Dx?
MS
98
Lhermitte phenomenon?
neck flexion = electric shock (MS)
99
Uhthoff's phenomenon?
burning after heat exposure (e.g. shower) (MS)
100
Optic neuritis?
painful red eye + sensitive to red (seen in MS)
101
Internuclear opthalmoplegia?
impaired lateral gaze (MS)
102
"Rice-water" stools?
cholera (Tx: IV fluids +/- ciprofloxacin)
103
Trosier's sign?
enlarged Virchow's node (i.e. left supraclavicular node) in GASTRIC CANCER
104
Lofgren's triad?
sarcoidosis 1) erythema nodosum 2) bilateral hilar lymphadenopathy 3) polyarthralgia
105
Charcot's neurologic triad?
MS 1) dysarthria 2) nystagmus 3) intention tremor
106
Coffee bean sign (on abdo X-ray)?
sigmoid volvulus
107
Wenkebach phenomenon?
Mobitz type I (2nd heart block)
108
Raindrop skull?
MM