Signs Flashcards
Kussmaul’s respiration?
DKA, hyperkalemia
(= hyperventilation)
Trousseau’s sign?
hypoparathyroidism, hypocalcemia
(= inflation of BP cuff above systolic pressure induces hand spasm)
Chvostek’s sign?
hypoparathyroidism, hypocalcemia
(= tap over facial nerve + look for spasm of facial muscles)
Beck’s triad?
pericardial effusion
(= falling BP, rising JVP, muffled heart sounds)
Quincke’s sign?
aortic regurgitation
(= capillary pulsation in nail beds)
De Musset’s sign?
aortic regurgitation
(= head nodding with each heartbeat)
Traube’s sign?
aortic regurgitation
(= pistol-shot sound when auscultating femoral artery)
malar flush?
mitral stenosis, SLE
(= pink patches on cheeks)
erythema marginatum?
rheumatic fever
(= redness of torso + inner limbs)
machinery murmur?
patent ductus arteriosus
clubbed blue toes with pink non-clubbed fingers?
patent ductus arteriosus
“hair on-end” X-ray?
beta thalassaemia
pain at McBurney’s point?
appendicitis
(= 2/3 away from umbilicus to ASIS)
fetor hepaticus?
liver failure
(= breath smells of rotten eggs)
Dupuytren’s contracture?
DM, liver failure
xanthelasma?
liver cirrhosis, DM
(= yellow fat deposits under skin around eyes)
liver flap/asterixis?
hepatic encephalopathy
(= flapping tremor with wrist extended)
Courvoisier’s sign?
if a patient with an enlarged gallbladder has painless jaundice, they don’t have gallstones
Murphy’s sign?
acute cholecystitis
(= pain on taking a deep breath when examiner places 2 fingers on RUQ)
Cullen’s sign?
acute pancreatitis
(= periumbilical bruising)
Grey Turner’s sign?
acute pancreatitis
(= left flank bruising)
Kayser-Fleischer ring?
Wilson’s disease
(= green-brown pigment in cornea)
PIZZ phenotype?
alpha-1 antitrypsin deficiency
(SOB from emphysema, cirrhosis, cholestatic jaundice)
Heberden’s nodes?
osteoarthritis
(= bone swellings at DIPJs)
Bouchard’s nodes?
osteoarthritis
(= bone swellings at PIPJs)
ulnar deviation?
rheumatoid arthritis
(= fingers deviate towards the ulnar side of the wrist)
swan neck (/Z thumb)?
rheumatoid arthritis
(= hyperextension of PIPJ + flexion of DIPJ)
Boutonniere deformity?
rheumatoid arthritis
(= flexion of PIPJ + hyperextension of DIPJ)
hammer toe deformity?
rheumatoid arthritis
(= 2nd/3rd/4th toe is bent at the middle joint so it resembles a hammer)
bamboo spine?
ankylosing spondylitis
(= fusion of spinous processes)
“telescopic fingers”?
psoriatic arthritis
(= bone shortening)
“pencil in cup” on X-ray?
psoriatic arthritis
Gottron’s papules?
dermatomyositis
(= scaly erythmatosus plaques over knuckles)
heliotrope eyelids?
dermatomyositis
(= purple eyelids)
“sunburst” appearance on X-ray?
osteosarcoma
(- soft tissue calcification)
Brudzinski’s sign?
meningitis + SAH
(= severe neck stiffness causes the patient’s hips + knees to flex when the neck is flexed)
Kernig’s sign?
meningitis, SAH
(= pain/resistance with passive extension of the knee)
psoas sign?
appendicitis
(= RIF pain on right hip flexion)
Rosvig’s sign?
appendicitis
(= palpation of LIF causes pain in RIF)
obturator sign?
appendicitis
(= RIF pain on right hip flexion + internal rotation)
Babinski’s sign?
UMN lesion
(= stimulation of the lateral plantar aspect of the foot causes dorsiflexion of big toe; causes plantar flexion in health)
frothy urine?
protein in urine (e.g. nephrotic syndrome)
“bag of worms” in scrotum?
varicoele
(= distended scrotal blood vessels)
bright white lemon-shape on CT?
extradural (/epidural) haemorrhage
dark sickle-shape on 1 hemisphere on CT?
subdural haemorrhage
bright white spherical shape on CT?
intracerebral haemorrhage
white star-shape on CT?
subarachnoid haemorrhage (SAH)
non-blanching petechial/purpuric rash?
meningitis
oligoclonal IgG bands on CSF examination?
multiple sclerosis
describe the parkinsonian gait
stooped posture, small steps, reduced arm swinging
> 35 CAG repeats on genetic testing?
Huntington’s disease
Jacksonian march?
focal epilepsy (in frontal lobe)
(= seizure “marches” up/down motor homunculus from face/thumb)
anti-AChR + anti-MUSK?
myasthenia gravis
anti-P/Q type VGCC Ab?
lambert eaton syndrome
wrist drop?
radial nerve (C5-T1) palsy
claw hand?
ulnar nerve (C7-T1) palsy
foot drop?
sciatic nerve (L4-S3) palsy (specifically the common peroneal branch)
flaccid paralysis?
LMN lesion
(= floppy)
spastic paralysis?
UMN lesion
(= tense)
“inverted champagne bottle” appearance of legs?
charcot-marie-tooth syndrome (CMT)
(= due to peroneal muscle atrophy of legs)
Gower’s sign?
Duchenne muscular dystrophy (DMD)
(= child uses hands on their legs to help them stand up; due to proximal muscle weakness in pelvis)
productive cough with khaki sputum?
bronchiectasis
“ground glass” appearance on HRCT of thorax?
interstitial lung disease (ILD)
lupus pernio?
sarcoidosis
(= raised, purple skin lesions on cheeks + nose)
crescentic glomeruli on kidney biopsy?
Goodpasture’s syndrome
“thumb sign” on lateral X-ray of neck?
acute epiglottitis
“barking” cough?
croup
periorbital purpura (/”panda eyes”)?
amyloidosis
“cobblestone” appearance of skin?
lymphoedema
Stemmer’s sign?
lymphoedema
(= skin at the bottom of the 2nd toe or middle finger can’t be pinched)
Whirlpool sign?
ovarian torsion
(= twisted vascular pedicle of ovaries)
villous atrophy + crypt hyperplasia?
Coeliac disease
what is Saint’s triad?
hiatus hernia, cholelithiasis, colonic diverticulosis
what is Reiter’s triad?
conjunctivitis, urethritis, arthritis
(reactive arthritis; “can’t see, can’t wee, can’t climb a tree”
pelvic/perineal pain lasting >3 months?
chronic prostatitis
(RFx: Trauma causing nerve damage in lower urinary tract)
what is Charcot’s triad?
fever, RUQ pain, jaundice
(ascending cholangitis)
low calcium, high phosphate, high uric acid, high potassium?
tumour lysis syndrome
spiral-shaped, gram -ve bacteria?
H.pylori
Tennis elbow?
lateral epicondylitis
Golfer’s elbow?
medial epicondylitis
CXR: “barrel chest”, flattened hemidiaphragm, cardiomegaly?
COPD
raised serum ACE + calcium?
sarcoidosis
SLE w/ skin involvement?
discoid lupus erythematosus
HLA-DR7?
antiphospholipid syndrome
HLA_DR2?
SLE
HLA-DR8?
ankylosing spondylitis
HLA-B27?
SpA
HLA-DR3?
Grave’s
HLA-DQ2, HLA-DQ8?
coeliac
HLA-DR4, HLA-DR5?
RA
CA-125?
ovarian cancer
(remember by “2” ovaries)
CA-19,9?
pancreatic cancer
(or oesophagus or bile ducts)
CEA?
colorectal cancer
(“CEA” looks like “caecum”)
HER-2?
breast cancer
BRCA?
breast cancer
AFP?
liver cancer
non-seminoma testicular cancer
Burning sensation whilst showering, tingling in hands + feet, + optic neuritis.
What is the most likely Dx?
MS
Lhermitte phenomenon?
neck flexion = electric shock
(MS)
Uhthoff’s phenomenon?
burning after heat exposure (e.g. shower)
(MS)
Optic neuritis?
painful red eye + sensitive to red
(seen in MS)
Internuclear opthalmoplegia?
impaired lateral gaze
(MS)
“Rice-water” stools?
cholera
(Tx: IV fluids +/- ciprofloxacin)
Trosier’s sign?
enlarged Virchow’s node (i.e. left supraclavicular node) in GASTRIC CANCER
Lofgren’s triad?
sarcoidosis
1) erythema nodosum
2) bilateral hilar lymphadenopathy
3) polyarthralgia
Charcot’s neurologic triad?
MS
1) dysarthria
2) nystagmus
3) intention tremor
Coffee bean sign (on abdo X-ray)?
sigmoid volvulus
Wenkebach phenomenon?
Mobitz type I (2nd heart block)
Raindrop skull?
MM